DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and K08F9.1

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	NP_506734.2	Gene:	K08F9.1 / 187167	WormBaseID:	WBGene00010684	Length:	490	Species:	Caenorhabditis elegans

Alignment Length:	491	Identity:	127/491 - (25%)
Similarity:	241/491 - (49%)	Gaps:	27/491 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGG 77
            |..::.:::.|...:|||..:.|..:....:||...:..|:...:|:..:|.::|..|::..:|.
Worm    10 LIVAVITSMAGSFHYGYNLVLTNPSQDAFLSFMNQTFAKRFDGGLSDHTLQNIWSFVVAVLFLGA 74

  Fly    78 MLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVP 142
            :.|.||..::|...|||.||.::..:|:....:...:|....:|:..:.|.::|.:..::..|..
Worm    75 LAGSFSIPFIAEGVGRKNGLYISISVGVLAGGMSIASKFIPLFELYIISRVVMGWSVSVSLGLSG 139

  Fly   143 MYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQLILLPV 207
            :::||.:|...||.:|.:...|:.:|.::..|:.:.||.||::.|.::....|...::....||.
Worm   140 IFLSEASPKQNRGAIGMMTGTAIQLGTVVGSVVAMPQIFGTDDLWWVIYATEIGIMLVFGAALPF 204

  Fly   208 CPESPRYLLITKQWEEEARKALRRLRASGSVEED--IEEMRAEERAQQSESHISTMELICSPTLR 270
            .||||.| ||.|...|.|..::.........|.|  ::|::.|:  ..|....:.:::|...:||
Worm   205 FPESPGY-LIQKGSLESATISISFYYKCEKEEADKHVKEIQKEQ--MNSTKKFTMLDVIQQKSLR 266

  Fly   271 PPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMDRTG 335
            ....:|.|:.....|||:..:..::..:.:::||....|..|......:.|:.::::|.::|:.|
Worm   267 DKAFVGAVVTFVMSFSGVAVISAFAFEILVNTGLNVLQASLANDATTIVSVISSVLAIAIIDKNG 331

  Fly   336 RRTLHLYGLGG-----MFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITA 395
            ||.|.|..|.|     :.||.:..|......::   :.::.:.....|..|||:|||.:.:.|.|
Worm   332 RRPLLLISLAGILICNLIIFGLMFTFDKFGNQV---LGFILIFFICIFQFFFALGPGPLSYFINA 393

  Fly   396 ELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTAL-ENYTFL-PFSVFLAIFWIFTYKKVPET 458
            ||..|..|.:|.:.|.:|..::.|.:...|..||..| |.:::| .|...:|:..:|.|..:|||
Worm   394 ELVGQDARSAAQSWASVVQMISQFSIITAFLPMKNQLGEAWSYLILFVAPVAVSLVFLYFSLPET 458

  Fly   459 KNKT-------FEEILALFRHNNGRSMLNCTNSLEP 487
            |||:       .||:..|....:.||     ||::|
Worm   459 KNKSPIEVEEAIEELPKLPLCRSTRS-----NSIKP 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	111/443 (25%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	120/467 (26%)
K08F9.1	NP_506734.2	MFS	13..461	CDD:391944	116/453 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010