DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut1 and slc2a15a

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	XP_017950703.2	Gene:	slc2a15a / 100494397	XenbaseID:	XB-GENE-992550	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	480	Identity:	185/480 - (38%)
Similarity:	279/480 - (58%)	Gaps:	4/480 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IFSAVLGML----QFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGG 77
            |.:||:|.|    .:|||..|:|||...|:....:.:..||...:|...|..|:||.||||||||
Frog    53 IMAAVVGALGSSFLYGYNLSVVNAPSVYIQELYNESWSARYNYTVSRGTISILWSVTVSIFAIGG 117

  Fly    78 MLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVP 142
            ::|......|.|..||||.:|||||..|..|.||..:.|:...||:.|||||:|::.|:..|.:|
Frog   118 LVGALIVIPMVNFLGRKGTMLLNNVFAITAALLMSLSNVAGIPEMMILGRFIMGIDGGIALSTLP 182

  Fly   143 MYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQLILLPV 207
            ||::|::|.::||.||.|..:.:.||:.:.||||:.::.|....||.|.|..:.||::||::||.
Frog   183 MYLNEVSPKHIRGSLGQVTAILICVGVFVGQVLGLPELFGKESQWPCLFGFIMIPALIQLVVLPF 247

  Fly   208 CPESPRYLLITKQWEEEARKALRRLRASGSVEEDIEEMRAEERAQQSESHISTMELICSPTLRPP 272
            .||||||||:.||..:.|.||.........|.:|||::.||.|.|::...:|..||..:.:::..
Frog   248 FPESPRYLLLEKQDRKRAEKAFCIFLGRNDVSQDIEDVLAETRIQRNLRLVSVPELFKTRSVKWQ 312

  Fly   273 LIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMDRTGRR 337
            :|..||...:.|..|:||:::|:.|:|..:|:..:...:.|:..|.|.::.:::|...::|.|||
Frog   313 IITVIVTMAAYQLCGLNAIWFYTNSIFSEAGIQPDKIPYITLSTGGIEILASVISGMTVERLGRR 377

  Fly   338 TLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGP 402
            .|.:.|.|.|.:|...:|:|...:....|:.|:|:|..||.:..|.:|||.||:::..|.|.|..
Frog   378 ILLIGGFGLMTLFFGILTVSLTFQHHAPWIPYISIVCILGVIASFCIGPGGIPFVLVGEFFQQSQ 442

  Fly   403 RPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEIL 467
            ||:|..||..|||::||.||:.||.::..|.||.||.|:.......::.|..:||||||||.||.
Frog   443 RPAAFMIAGSVNWISNFAVGLLFPLIQEGLGNYCFLIFAAICLAGTLYLYFILPETKNKTFSEID 507

  Fly   468 ALFRHNNGRSMLNCTNSLEPQSMNS 492
            ..|...||.|.....|.:.|....|
Frog   508 QAFAKMNGISSATKGNEIHPTEETS 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	167/438 (38%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	177/455 (39%)
slc2a15a	XP_017950703.2	MFS_GLUT_Class2	55..506	CDD:340990	175/450 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010