DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Glut1 and LOC100334818

DIOPT Version :9

Sequence 1:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster
Sequence 2:	XP_002665301.2	Gene:	LOC100334818 / 100334818	-ID:	-	Length:	484	Species:	Danio rerio

Alignment Length:	475	Identity:	189/475 - (39%)
Similarity:	282/475 - (59%)	Gaps:	5/475 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIF 73
            ||..|..||.:||||.||.||.||.||.|.:.||.|....::.|:.:.|.:..:..|:|::|||.
Zfish     8 LTLPLLTSIVAAVLGSLQIGYQTGNINPPARVIEEFFNTTWRSRHNQSIPDHSLTFLWSLSVSIK 72

  Fly    74 AIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNT 138
            ..|.:||......:|:.|||:..:|:.|.|.:|||.||..::.:.|:|:|.:||.|.|:.|||..
Zfish    73 DFGALLGSLGVKGLADTFGRRNAILIANALSVAGASLMFMSEATASFEVLIVGRLIFGLFCGLVM 137

  Fly   139 SLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQLI 203
            ||.|:||..::|.||||...|:||:....|:||..|:|:|.:|||.:.|.::|.|::.||.||.:
Zfish   138 SLNPLYIQGVSPTNLRGAFATLNQVFFASGILLGMVVGLETVLGTEKYWSLMLSLSLIPATLQYL 202

  Fly   204 LLPVCPESPRYLLITKQWEEEARKALRRLRASGS-VEEDIEEMRAEERAQQSESHISTMELICSP 267
            .||.||||||||.|.:..||||..||||||.:.. |.:::||||  |.|..||:.::..|.:...
Zfish   203 TLPFCPESPRYLFINRGKEEEAEAALRRLRGNPEMVMKEMEEMR--EEAAHSETGVTVREFLRKR 265

  Fly   268 TLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMD 332
            ..|.|:|:.:::.|..|.||.||:..|||.:|..|...|  |.:.|:|:||:.|..|:|:..|::
Zfish   266 RYRQPIILVLIINLGSQLSGFNAIINYSTKMFAQSNFDE--ATYLTLGVGAVNVAFTIVAFFLVE 328

  Fly   333 RTGRRTLHLYGLGGMFIFSIFITISFLIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAEL 397
            |.|||.|.|.|...:.|.::.:||::.|..::.::..:.|:.....:..:.||||.|.|.|.|||
Zfish   329 RAGRRKLLLAGFLSLAICNLLMTITYSILTIVPFIRNIQVLVVFFLISAYEVGPGPISWFIAAEL 393

  Fly   398 FSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPETKNKT 462
            |.|..||.|||...::||...||:.:.||.:......|.:|.|.....:.:.:|..::||||.:|
Zfish   394 FDQSARPIAMAFTSMLNWGGKFVLALLFPPLLKICGAYVYLLFMCMALLAFTYTMFRLPETKGRT 458

  Fly   463 FEEILALFRHNNGRSMLNCT 482
            |::|.|.||...|..:.|.|
Zfish   459 FDDIAAEFRGAEGIPLHNKT 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut1	NP_612073.2	MFS	17..452	CDD:119392	171/435 (39%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	179/452 (40%)
LOC100334818	XP_002665301.2	Sugar_tr	19..466	CDD:278511	179/450 (40%)
LOC100334818	XP_002665301.2	MFS	66..449	CDD:119392	152/386 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.920