Protein Alignment CG13907 and SLC16A6

DIOPT Version :10

• Sequence 1: NP_612069.1
• Gene: CG13907 / 38104
• FlyBaseID: FBgn0035173
• Length: 816
• Species: Drosophila melanogaster
• Sequence 2: XP_024306789.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 542
• Species: Homo sapiens
• Alignment Length: 722
• Identity: 155/722 - (21%)
• Similarity: 256/722 - (35%)
• Gaps: 243/722 - (33%)

  Fly    63 SVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKGTVAWVGSLLSGVY 127
            :||.|:   ||||:||.:..:.|...:...||..|||:|..:.:..|:|....::|:.|:...|.
Human    32 NVYTEV---PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVL 93

  Fly   128 LSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVA 192
            ..:.|:.:.|:|::|.|.|.:.|.::.....|.::||..||.:....|.:.|.|:...:||.|..
Human    94 TFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTI 158

  Fly   193 VGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLI-LNCAIFGAMMRPL 256
            :..||..:||:.|.:|..|..|..|||||....|.|..||:.:|| |.||: ||..||||::||:
Human   159 LSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLL-FVGLLQLNIVIFGALLRPI 222

  Fly   257 TYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNA-DPGVHSSLNLEL 320
            ........|.::|...:|.|..||                  ..|.:..::: |.||.
Human   223 FIRGPASPKIVIQENRKEAQYMLE------------------NEKTRTSIDSIDSGVE------- 262

  Fly   321 LAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESE 385
                        ::|.|                                               :
Human   263 ------------LTTSP-----------------------------------------------K 268

  Fly   386 NSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLE 450
            |.|.|:...:...|.....|.                    |||.
Human   269 NVPTHTNLELEPKADMQQVLV--------------------KTSP-------------------- 293

  Fly   451 AGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLS 515
                                          ||..:|
Human   294 ------------------------------RPSEKK----------------------------- 299

  Fly   516 LTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNI 580
                                         .|              :||.|:||:..|:...:..:
Human   300 -----------------------------AP--------------LLDFSILKEKSFICYALFGL 321

  Fly   581 FGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNSLLLNNCCLL 645
            |...|.:.|.:|::.......|.::.||.|||.:.|....||:..|:|.:...:..:.:...|::
Human   322 FATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVI 386

  Fly   646 VSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILV---DLLGLDKLTNAFGLLILFRGF 707
            :.|:::........:...::.|||||..: |.|..|.|.|:   |::|::|:::|.|:.|..:..
Human   387 LLTVSLFAFTFATEFWGLMSCSIFFGFMV-GTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSI 450

  Fly   708 AALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTI-TSFLAPC---LKRCSPSEETPV---HVET 765
            |.|.|.||||.:.|.:..|...||...|...::.: .:.:.||   |.:...|.||.|   ..:|
Human   451 AGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKT 515

  Fly   766 LTPIDEE 772
            |..|.|:
Human   516 LQDIPED 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13907	NP_612069.1	MFS_MCT_SLC16	77..>260	CDD:340910	62/183 (34%)
		MFS	<566..748	CDD:475125	48/185 (26%)
SLC16A6	XP_024306789.2	MFS_MCT7	43..491	CDD:340980	137/675 (20%)