Protein Alignment CG13907 and Slc16a8

DIOPT Version :10

• Sequence 1: NP_612069.1
• Gene: CG13907 / 38104
• FlyBaseID: FBgn0035173
• Length: 816
• Species: Drosophila melanogaster
• Sequence 2: NP_113932.2
• Gene: Slc16a8 / 65200
• RGDID: 69282
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 770
• Identity: 165/770 - (21%)
• Similarity: 250/770 - (32%)
• Gaps: 328/770 - (42%)

  Fly    71 PPDGGYGWVICFASFMCNMIVDGIAYTF----GIFLEEFVAYFHEGKGTVAWVGSLLSGVYLSAG 131
            |||||:|||:..|.|    ::.|.||.|    .:|..|....|..|....|||.|::..:....|
  Rat    12 PPDGGWGWVVLGACF----VITGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTG 72

  Fly   132 PIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYY 196
            |:.|.|..::|||.|.:||.::|....:|::|::.:..|..|.|.:.|.|..:.:.|:::.:|.|
  Rat    73 PLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLY 137

  Fly   197 FETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKK 261
            ||.:|.||.|:|..||.......:||...|.|.:||:...|:|.||:|:|...||:|||   |..
  Rat   138 FERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRP---PPG 199

  Fly   262 KKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAG 326
            .:.:|                                          ||
  Rat   200 PQPRP------------------------------------------DP---------------- 206

  Fly   327 GGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHS 391
                                        :||.|
  Rat   207 ----------------------------APPGG-------------------------------- 211

  Fly   392 QDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGD 456
                                                              ||
  Rat   212 --------------------------------------------------RA------------- 213

  Fly   457 FASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEK 521
                                                                             
  Rat   214 ----------------------------------------------------------------- 213

  Fly   522 SMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGL 586
                           :||:                    :||:::..|..||:..|:......||
  Rat   214 ---------------RHRQ--------------------LLDLAVCTDRTFMVYMVTKFLMALGL 243

  Fly   587 YVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADL----PQVNSLLLNNCCLLVS 647
            :||.:.||:.||:..:|..:||.||||:|..:.|.|..||.:|.|    |.|..|.  :..||.:
  Rat   244 FVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLF--SLALLAN 306

  Fly   648 TIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIG 712
            .:...::....||...:...|.|||:.....:|...:|:..:|..:..:|.||::|....|.|||
  Rat   307 GLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIG 371

  Fly   713 TPLAGAIYDMTHTYDLPFYMAGA---LFGI-STITSFLAPCLKRCS------PSEETPVHVETLT 767
            .|.||.:.|....|::.||:||:   |.|: ..:|::   |.:|||      ||.|....
  Rat   372 PPSAGRLVDALKNYEIIFYLAGSEVVLAGVFMAVTTY---CCQRCSKDIPPGPSAEGGTS----- 428

  Fly   768 PIDEEQGEDAEDDEDQPI-TIVPKIIKTL-------ASPQQEEGHPQFPQKTSES 814
              |.|..|...|.|..|. |..|..::.|       .||:.||  ...|..:.||
  Rat   429 --DTEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEPEE--EAVPDLSHES 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13907	NP_612069.1	MFS_MCT_SLC16	77..>260	CDD:340910	64/186 (34%)
		MFS	<566..748	CDD:475125	60/189 (32%)
Slc16a8	NP_113932.2	2A0113	14..440	CDD:273325	151/725 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..490		19/70 (27%)
		Basolateral sorting signal. /evidence=ECO:0000250|UniProtKB:O95907	426..460		9/40 (23%)
		Basolateral sorting signal. /evidence=ECO:0000250|UniProtKB:O95907	461..480		7/21 (33%)