Protein Alignment CG13907 and mct-2

DIOPT Version :10

• Sequence 1: NP_612069.1
• Gene: CG13907 / 38104
• FlyBaseID: FBgn0035173
• Length: 816
• Species: Drosophila melanogaster
• Sequence 2: NP_503681.2
• Gene: mct-2 / 182056
• WormBaseID: WBGene00015273
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 719
• Identity: 198/719 - (27%)
• Similarity: 302/719 - (42%)
• Gaps: 230/719 - (31%)

  Fly    56 EDDDDEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFG-----IFLEEFVAYFHEGKGT 115
            |:.:::....|:: .|||||||||:..|||:.||.|||:.||.|     |:.::|      |..:
 Worm    25 ENFEEQVEEVGKV-TPPDGGYGWVVVAASFLVNMAVDGVIYTCGKILVPIWADQF------GSTS 82

  Fly   116 VAW-VGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGG 179
            ||. |.|:|:|.|..|||:.|:..|.:|.|:|.|||||:|..||:||.|::.:..|...:|.:||
 Worm    83 VAGAVISILTGCYYLAGPLASSFVNVFGIRSVAIAGSILATTAFLLSRFASTIWELYLLFGVLGG 147

  Fly   180 FGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFA----PLATYLLEEYGWKNALLIFA 240
            .|||.:|||::|.:..||..|||:||||||||||.||..|:    |:..|..::.|  :.::..|
 Worm   148 IGFGCMYLPSIVILSTYFAKKRSVATGIAVCGSGIGTMVFSTINGPVFDYFGKDVG--SFMVYLA 210

  Fly   241 GLILNCAIFGAMMRPL---TYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKL 302
            .:.::.::|..:..||   .:..||..|  |.|.||.|                  |:...:|.|
 Worm   211 AIAISGSLFSLLFAPLKATEHQVKKVAK--MVRNYEGK------------------PEEPTQRLL 255

  Fly   303 KMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSA 367
            :                                          ||
 Worm   256 E------------------------------------------DV-------------------- 258

  Fly   368 RSAAGAVGRRPHRNS-ESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSAS 431
                        ||. |..|.|.|:.|         .|.||   :.|.:.|  ..||..||.:.|
 Worm   259 ------------RNDLEELNRPGHNAD---------TFYAG---NAPVSRS--RSNTLDRKAAES 297

  Fly   432 ERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTN 496
            ....    .:.||..                               ..|..:.:|..|
 Worm   298 AEAH----VVHATEH-------------------------------HTVHHVVKKSKF------- 320

  Fly   497 LPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTM 561
                                ||:::|:.||
 Worm   321 --------------------TKFKESLCSV----------------------------------- 330

  Fly   562 LDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLL--SIIGITNTVGRVF 624
            ||..||..|.||.:.||..|.:....||||||..|.|:.:....||.:.|  ::||..|.:.|:.
 Worm   331 LDKDLLFSPSFMTLAVSGTFTVLSFLVPFVYLALAMKQKNPDFTDAELSLPVTLIGAFNIMFRIG 395

  Fly   625 CGWVADLPQVNSLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLL 689
            ||.|||.|::::|.::|...:::..::...|.|.....|:...|.|...::.:.:|.|:|.|:|:
 Worm   396 CGMVADHPKMSALQVSNVATIIAGTSMLFVPFCTELWHYVVFCIPFSAGVACFAALRSVICVELI 460

  Fly   690 GLDKLTNAFGLLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCS 754
            |::||:||||:|::|.|..|::|.|:|..|.|:|..||:.||:.|.:|..|.:.:...|.||...
 Worm   461 GVEKLSNAFGILMVFMGIGAVVGGPIAAQIKDITGNYDISFYVMGIIFAFSGVMTIRLPELKAWE 525

  Fly   755 PSEE 758
            .|::
 Worm   526 ESKK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13907	NP_612069.1	MFS_MCT_SLC16	77..>260	CDD:340910	79/195 (41%)
		MFS	<566..748	CDD:475125	65/183 (36%)
mct-2	NP_503681.2	MFS_MCT_SLC16	45..519	CDD:340910	186/686 (27%)