DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Usp10 and UBP15

DIOPT Version :9

Sequence 1:	NP_001261229.1	Gene:	Usp10 / 38103	FlyBaseID:	FBgn0052479	Length:	1517	Species:	Drosophila melanogaster
Sequence 2:	NP_001185019.1	Gene:	UBP15 / 838281	AraportID:	AT1G17110	Length:	928	Species:	Arabidopsis thaliana

Alignment Length:	841	Identity:	161/841 - (19%)
Similarity:	276/841 - (32%)	Gaps:	274/841 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   681 PSQQYNQAQQQQVRRKYSSEYNHHHHQHGSSDTGIQTTKTMSWTNSAQHKKSTQSV---SVTASP 742
            |.:..:.:.::....|.|..|:|      ..|:.:.:..|   |.:|:.|.|..||   |:..|.
plant   169 PVESCSSSSERVSFEKDSVLYDH------GMDSTMYSNNT---TQAAKGKTSKSSVDFASLGISQ 224

  Fly   743 NSVN---NGPGVGAAGKANYSHTTKTFTNQQHYQQQHYHTQNSYNNNSSGGGSSSNSSSSSSNNQ 804
            |.:.   |..|..:.||   .|::|  .|::..::......:|.:..:|.||.:..|.
plant   225 NDITPQINTQGRKSVGK---QHSSK--ANRESCRRDSATVFDSSDEAASAGGDNKTSH------- 277

  Fly   805 PQVRNYGTMKMPSSPVAWTAPTPERKNSQQAAAAPAAATASAAPVAITTVTTSTASITAT---PN 866
                    :|..|...::.|.|..|::|..::|......:..:.:..:....:...:.::   ||
plant   278 --------IKHKSRGNSYAAETNPRRHSVDSSAVQMNGQSFVSGMQESHKHENNLGVRSSFGCPN 334

  Fly   867 QFQPETGSSSAS-PAVAAAQQQQPAAQQHAQAAQTGAAAAPSKSHSNYASSKKHQSYEPVVLSSV 930
            ...|..|:.:|: |....   .:...|...:.::.|..||.||:                |.|..
plant   335 TQYPSNGTRTATLPRTGI---NKSGEQSCTETSKKGQVAAVSKT----------------VRSKD 380

  Fly   931 VATSSSANPQPQLNLAPPAPPASQNSSDSSQLSWASLFASNKPVAKVAPYEASKIAQQQPSHPVL 995
            ...|..:|                  ..||.:....:............|:..|::.       |
plant   381 TGISEESN------------------GISSTMGIMKMMGLRNSTKHDDRYKNLKVSS-------L 420

  Fly   996 QLAPPQPAQVAAAAPVAQLSSPPQNLPLPTAHQQSQLPAPVPAPTAPLVTPGALSYSAASAQAVP 1060
            .|.|
plant   421 MLFP------------------------------------------------------------- 424

  Fly  1061 APSPASASVKPLKPEPPRPVQQQLDEWTSKYAEYLTRHKTNLASISLRPRGLTNRSNYCYINSIL 1125
                                          |.|:|...:..:..:|  ||||.|..|.||.|::|
plant   425 ------------------------------YEEFLKFFQCEVFDLS--PRGLVNCGNSCYANAVL 457

  Fly  1126 QALLGCSPF--YNLLRSIPKQAA-----VLSEVKTPTVNAMMSFMTNFSSLPSGLRLRLNNLNKG 1183
            |:|....|.  |.|.||..:..:     ::.|::...:      |...|..|......|:::.
plant   458 QSLTCTKPLVAYLLRRSHSRSCSGKDWCLMCELEQHVM------MLRESGGPLSASRILSHMR-- 514

  Fly  1184 SQSKGKDDFVGSDLQCDMAFEPTEIYKLWNDSREEHVEGRQEDAEEFLGYVLNKLNDEMLEVIKL 1248
                        .:.|.:.                  :|.||||.|||..::..:....||
plant   515 ------------SINCQIG------------------DGSQEDAHEFLRLLVASMQSICLE---- 545

  Fly  1249 IDKPTPQQNGQEPAEPEDGGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGELRSRLQ-REGEH 1312
                  :..|:...:|.                  .::|    |.|..:|.|.|||::: ...:|
plant   546 ------RLGGETKVDPR------------------LQET----TLVQHMFGGRLRSKVKCLRCDH 582

  Fly  1313 STDVIQPFFTLQLNIEK-AASVKEALEILVGRDQLEG---VTGSKTKQEVVAWQQMTLEKLPVVL 1373
            .::..:....|.|.|.. ..|:::||......:.|:|   ...|:....|.|.:::::.:.|.:|
plant   583 ESERYENIMDLTLEIYGWVESLQDALTQFTRPEDLDGENMYRCSRCAGYVRARKELSIHEAPNIL 647

  Fly  1374 ILHLKYFDYRSDGCTKILKKVDFPVELKIDAKILGSKKTSQKQRAYRLFAVVYH-DGKEAS-KGH 1436
            .:.||.|.....|  ||.|.:.||..|.:   |....:|......|.|:||:.| |...|| .||
plant   648 TIVLKRFQEGRYG--KINKCISFPEMLDM---IPFMTRTGDVPPLYMLYAVIVHLDTLNASFSGH 707

  Fly  1437 YITDVFHTGYSSWLRYDDSSVKPVSEKHVLQPHTPRVPYLLYYRRSDTLPPQQQQTQQQNG 1497
            ||:.|... ..:|.|.|||.:.||....|:....    |:|:|.||...|    |..:.||
plant   708 YISYVKDL-RGNWYRIDDSEIHPVPMTQVMSEGA----YMLFYMRSYPRP----QRGEHNG 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_001261229.1	UCH	1109..1479	CDD:278850	92/383 (24%)
Usp10	NP_001261229.1	Peptidase_C19	1223..1480	CDD:239072	68/263 (26%)
UBP15	NP_001185019.1	zf-MYND	130..167	CDD:280009
		Peptidase_C19E	441..746	CDD:239126	92/384 (24%)
		UCH	441..745	CDD:278850	92/383 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910