Protein Alignment Usp10 and USP9X

DIOPT Version :9

• Sequence 1: NP_001261229.1
• Gene: Usp10 / 38103
• FlyBaseID: FBgn0052479
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_005272732.1
• Gene: USP9X / 8239
• HGNCID: 12632
• Length: 2575
• Species: Homo sapiens
• Alignment Length: 536
• Identity: 112/536 - (20%)
• Similarity: 182/536 - (33%)
• Gaps: 174/536 - (32%)

  Fly  1064 PASASVKPLKPEPP-----------------RPVQQQLDEWTSKY--------AEYLTRHKTNLA 1103
            ||..:: |:...||                 |.::|.:|..|..|        .|.||..: .|.
Human  1489 PAEQAI-PVCGSPPTINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWE-YLP 1551

  Fly  1104 SISLRPR----GLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVL-----------SEVKT 1153
            .:..||.    ||.|....||:||::|.|.......|.:.:|....:.:           :|...
Human  1552 PVGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNV 1616

  Fly  1154 PTVNAMMSFMTNFSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQC---DMAFEPTEIY------ 1209
            ...:.:..:...|...|:        |:|....|..:..|...||.   .:|....:.|
Human  1617 DPRDDVFGYPQQFEDKPA--------LSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFW 1673

  Fly  1210 ---KLWNDS---REEHVEGRQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAEPEDGG 1268
               :||.:.   ||:|      ||.||    .|.|.|.:.|.:|.:..|
Human  1674 KQFRLWGEPVNLREQH------DALEF----FNSLVDSLDEALKALGHP---------------- 1712

  Fly  1269 DVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGELRSRLQREG-EHSTDVIQPFFTLQLNIEKAAS 1332
                                   ..:|.:..|....:...:| .|..:..:.|.||.::|....:
Human  1713 -----------------------AMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQN 1754

  Fly  1333 VKEALEILVGRDQLEGVTG---SKTKQEVVAWQQMTLEKLPVVLILHLKYFDY--RSDGCTKILK 1392
            :.::||..|..|.|||...   .|..::|...:::.::|||.||.:.||.|||  ..:...|...
Human  1755 LLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFND 1819

  Fly  1393 KVDFPVELKID-------AKILGSKKTSQKQ---------------RAYRLFAVVYHDGKEASKG 1435
            ..:||.||.::       ||:.|.....:.|               ..|||..|:.|.| :||.|
Human  1820 YFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTKYRLVGVLVHSG-QASGG 1883

  Fly  1436 HYITDVFHTG-----YSSWLRYDDSSVKPVSE--------------------KHVLQPHTPR--- 1472
            ||.:.:....     .:.|.::||..|.....                    .|:::..:.|
Human  1884 HYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQK 1948

  Fly  1473 ---VPYLLYYRRSDTL 1485
               ..|:|:|.|.||:
Human  1949 RWWNAYILFYERMDTI 1964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_001261229.1	UCH	1109..1479	CDD:278850	93/458 (20%)
		Peptidase_C19	1223..1480	CDD:239072	65/315 (21%)
USP9X	XP_005272732.1	peptidase_C19C	1560..1963	CDD:239124	94/460 (20%)
		UCH	1562..1958	CDD:278850	92/453 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D625455at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010