Protein Alignment Usp10 and usp9

DIOPT Version :10

• Sequence 1: NP_728554.1
• Gene: Usp10 / 38103
• FlyBaseID: FBgn0052479
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_005167793.1
• Gene: usp9 / 568683
• ZFINID: ZDB-GENE-061019-1
• Length: 2594
• Species: Danio rerio
• Alignment Length: 531
• Identity: 118/531 - (22%)
• Similarity: 188/531 - (35%)
• Gaps: 161/531 - (30%)

  Fly  1057 QAVPAPS-PASAS-----VKPLKPEPPRPVQQQLDEWTSKY---AEYLTRHKTNLASISLRPR-- 1110
            ||:|..| ||:.:     :..|.....|.::|.:|..|..|   .|.||..: .|..:..||.
Zfish  1491 QAIPVCSTPATINAGFELLVALAIGCVRNLKQIVDTLTDMYYLGCEPLTEWE-YLPPVGPRPTKG 1554

  Fly  1111 --GLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVL-----------SEVKTPTVNAMMSF 1162
              ||.|....||:||::|.|....|..|.:.:|....:.:           :|......:.:..:
Zfish  1555 FVGLKNAGATCYMNSVIQQLYMIPPIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDEVFGY 1619

  Fly  1163 MTNFSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQC---DMAFEPTEIY---------KLWNDS 1215
            ...|...||        |:|....|..:..|...||.   .:|....:.|         :||.:.
Zfish  1620 QHQFDDKPS--------LSKSEDRKEYNIGVLRQLQVIFGHLASSRLQYYVPRGFWKQFRLWGEP 1676

  Fly  1216 ---REEHVEGRQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAEPEDGGDVWQMICNN 1277
               ||:|      ||.||    .|.|.|.:.|.:|.:..|
Zfish  1677 VNLREQH------DALEF----FNSLVDSLDEALKALGHP------------------------- 1706

  Fly  1278 RNKGSVTRQTDFGRTPVSDIFRGELRSRLQREG-EHSTDVIQPFFTLQLNIEKAASVKEALEILV 1341
                          ..:|.:..|....:...:| .|..:..:.|.||.::|....::.:::|..|
Zfish  1707 --------------AMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSMEQYV 1757

  Fly  1342 GRDQLEGVTG---SKTKQEVVAWQQMTLEKLPVVLILHLKYFDY--RSDGCTKILKKVDFPVELK 1401
            ..|.|||...   .|..::|...:::.::|||.||.:.||.|||  ..:...|.....:||.||.
Zfish  1758 KGDLLEGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELD 1822

  Fly  1402 ID-------AKILGSKKTSQKQR-----------------AYRLFAVVYHDGKEASKGHYITDVF 1442
            ::       ||:.||....:.|:                 .|||..|:.|.| :||.|||.:.:.
Zfish  1823 MEPYTVAGVAKLEGSDVHPENQQQVIQQNEPSEPEPPCSSRYRLVGVLVHSG-QASGGHYYSYII 1886

  Fly  1443 HTGYSS-------WLRYDDSSVKPVSE--------------------KHVLQPHTPR------VP 1474
            ....|.       |.::||..|.....                    .|:::..:.|      ..
Zfish  1887 QRNGSGGEGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNA 1951

  Fly  1475 YLLYYRRSDTL 1485
            |:|:|.|.|||
Zfish  1952 YILFYERMDTL 1962

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_728554.1	UCH	1110..1479	CDD:425685	95/461 (21%)
usp9	XP_005167793.1	Ubl1_cv_Nsp3_N-like	881..964	CDD:475130
		peptidase_C19C	1554..1961	CDD:239124	97/464 (21%)
		DUF3517	2100..2479	CDD:463438
		PRK10263	<2492..>2591	CDD:236669