DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp10 and nelfa

DIOPT Version :9

Sequence 1:	NP_001261229.1	Gene:	Usp10 / 38103	FlyBaseID:	FBgn0052479	Length:	1517	Species:	Drosophila melanogaster
Sequence 2:	NP_001166972.1	Gene:	nelfa / 559677	ZFINID:	ZDB-GENE-030131-6400	Length:	542	Species:	Danio rerio

Alignment Length:	337	Identity:	68/337 - (20%)
Similarity:	103/337 - (30%)	Gaps:	91/337 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   805 PQVRNYGTMKMPSSPV----AWTAPTPERKNSQQAAAAPAAATASAAPVAITTVTTSTASI---- 861
            |.::::...:.|.|..    .....|...:..::.|..|..:........|.| ||....|
Zfish   158 PPIKHFQLKRKPKSATLRAELLQKSTETAQQLKKTAGVPFHSKGRGLVKKIDT-TTPLKGIPKAP 221

  Fly   862 ---TATPNQFQPETGSSSASPAVAAAQQQQPA----------------AQQHAQAAQTGAAAAPS 907
               ..||:.|.|.:..:..:||....::::..                |::..:...|.|....:
Zfish   222 FRSPTTPSMFSPPSNRTPIAPARTPLRKERGVKLLDISELDMVGAGREAKRRRKTLDTEAGEKAA 286

  Fly   908 KSHS----------------------NYASSKKHQSYEPVVLSSVVATS---------------- 934
            |..:                      |..|:....||.|...|.|.::|
Zfish   287 KEEAVVENATPDYAAGLVSTQKLGALNNESALPSTSYLPATPSMVPSSSYIPSSETQPANAGGSG 351

  Fly   935 -SSANPQPQLNLAPPAPPASQNSSDSSQLSWASLFASNKPVAKVAPYEASKIAQQQPSHPVLQLA 998
             .:.|.|.:.:.||.|..||....          |....|:     |.||..:...|:.|....:
Zfish   352 RETTNRQSEESAAPSAAAASLPGQ----------FKQRPPM-----YNASTASPTAPTSPTTPTS 401

  Fly   999 PPQPAQVAAAAPVAQLSSPPQNLPLPTAHQQSQLPAPVPAPTAPLVTPGALSYSAASAQAVPAPS 1063
            .|.......||..||...|.|  |..||.|    |||.|||  |...| ..:.|....|...|..
Zfish   402 TPTNNGPPPAATAAQPDMPTQ--PPTTAAQ----PAPTPAP--PQTQP-KKNLSLTREQMYAAQE 457

  Fly  1064 PASASVKPLKPE 1075
            ....:.|..:||
Zfish   458 MFKTANKVTRPE 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Usp10	NP_001261229.1	UCH	1109..1479	CDD:278850
Usp10	NP_001261229.1	Peptidase_C19	1223..1480	CDD:239072
nelfa	NP_001166972.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13328
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100