Protein Alignment Usp10 and puf

DIOPT Version :9

• Sequence 1: NP_001261229.1
• Gene: Usp10 / 38103
• FlyBaseID: FBgn0052479
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Alignment Length: 1212
• Identity: 213/1212 - (17%)
• Similarity: 380/1212 - (31%)
• Gaps: 375/1212 - (30%)

  Fly   482 PALLPPPPHHILQQTSPLLIEQP---------AQLVQAQPPQPPTPTPQQQQQQQHQEQ------ 531
            |::|||||...|   ..:|:.||         .|.:....||..|..||...:.|...:
  Fly  1357 PSMLPPPPKECL---PTVLLLQPKYFEKLFCLMQTLGDMQPQASTVNPQHHTKAQLLSRRVWDIL 1418

  Fly   532 ----------TADKSLTQNNNEVVALD-----EKLANEKQQQIDFHQQQQEQQQQQQQQQQQQQL 581
                      .|.|||..:.:|:..||     |:||.:::|   ..|:.::.......|:....|
  Fly  1419 AMLPTNPHILDAFKSLVTDLSELEQLDAGGEEEQLATKRKQ---IKQKFRDLLDPNNLQKFMYSL 1480

  Fly   582 H-----PLAQQQQQEEQ------QQPQQLQPLQTEKPPTKVPNLVVATVAPQLQQPPLQQHQQQQ 635
            |     .|...::.|..      ..|:|::..::.....:..|          :|||       .
  Fly  1481 HIVESLALTSSRRGESNGNVAMGNTPEQVRVKKSSMGRRRNSN----------EQPP-------P 1528

  Fly   636 TSPVVVSPKQQQQQSQAAHQNSYHDQHPLPQQQQPQQQQPQPQRKPS---QQYNQAQQQQVRRKY 697
            ..|.|...|:|..:.:|          ||........|..:.:...|   .:.||.:|...|:|.
  Fly  1529 PPPEVKMSKEQLCELEA----------PLTPTPSTGLQDVETEASSSSGGDKENQPKQHSKRQKK 1583

  Fly   698 SSEYNHHHHQHGSSDTGIQTTKTMSWTNSAQHKKSTQSVSVTASPNSVNNGPGVGAAGKANYS-- 760
            ...:.                         |.|:.....|...||........|...|...:|
  Fly  1584 GETFE-------------------------QEKERPVGCSTPPSPTPPPPALSVVERGDNKWSEA 1623

  Fly   761 --------HTTKTFTNQQHYQQQHYH--TQNSYNNNS----------SGGGSSSNSSSSSSNNQP 805
                    |..:.|:..|..|..|..  ..|.:.::.          .|.....::.:....::|
  Fly  1624 FVKCGGLRHLYEIFSEGQLQQSAHPKELALNEWRHDCLASLLRILWLLGFEELQSADAHVLMSRP 1688

  Fly   806 QVRNYGTMKMPSSPVAWTAPTPERKNSQQAAAAPAAATASAAPVAITTVTTSTASITATPNQFQP 870
            .......|::|......::...:..:.|..|       :||.|:..             |.|||.
  Fly  1689 HPFMLQLMEVPQCLTRLSSILNDEVHQQHQA-------SSANPLVF-------------PYQFQH 1733

  Fly   871 -ETGSSSASPAVAAAQQQQPAAQQHAQAAQTGAAAAPS-KSHSNYASSKKHQSYEPVVLSSVVA- 932
             .||....:..:..|.... .:..||.|.......||: ..|..:......:..||.|...:.|
  Fly  1734 LRTGFWGRAQLIQFAMNIL-VSFVHASAEARRLLWAPTGTDHCRWLQKFILEDPEPAVRREICAG 1797

  Fly   933 ----TSSSANPQPQLNLAP-------PAPPASQNSSDSSQLSWASLFASNKP-----------VA 975
                ...:|:.. :|.|||       ..|.|.|.||.:....:........|           :|
  Fly  1798 LYRICLGNAHSY-RLLLAPLLHKLIALLPLAEQMSSGNQHTQFLLSEEGKDPYGPACRDYFWLLA 1861

  Fly   976 KVAPYEASKIAQQQPSHPVLQLAPPQPAQVAAAAPVAQLSSPPQNLPL-PTAHQQSQLPAPVPAP 1039
            ::....:.::..::  |..:::.....:|........:|....|:..| ...:..|.|   :...
  Fly  1862 RLVDTLSPEMVAEE--HIDIEMLCESISQSILTREYYELRHGYQDDGLVGLLNLMSNL---IKYD 1921

  Fly  1040 TAPLVTPGALSYSAASAQAV----PAPSPASASVKPLKPEPPRPVQQQL---------DEWTSKY 1091
            |....||.|||:   ..|.:    ..||||.......|....|.....|         ..:...:
  Fly  1922 TTFKYTPKALSF---IEQLIGFLFDMPSPADRQKPKCKSASSRASAYDLLVELCRGCATNYAYLH 1983

  Fly  1092 AEYLTRHKTNLASISLRPR--------------------GLTNRSNYCYINSILQALLGCSPFYN 1136
            ...|.:||:.       |:                    ||||....||:.|.:|.|........
  Fly  1984 GRLLAQHKSG-------PKQPYPWDYWPRDEGRAECGYVGLTNLGATCYMASCVQHLYMMPQARA 2041

  Fly  1137 LLRSIPKQAAVLSEVKTPTVNAMMSFMTNFSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDM 1201
            .:..:|..||   ....||   ::.....|:.|              .:|:.|
  Fly  2042 AVLRVPPNAA---RKHGPT---LLELQRMFAYL--------------LESERK------------ 2074

  Fly  1202 AFEPTEIYKLWNDSREEHVEGRQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAEPED 1266
            ::.|....:::....:....|.|:|..||...:::||.|...::..|:.:
  Fly  2075 SYNPRSFCRVYQMDHQPLNTGEQKDMAEFFIDLVSKLEDMTPDLKHLVKR--------------- 2124

  Fly  1267 GGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGELRSRLQREGEHSTDVIQPFFTLQLNIEKAA 1331
                  :.|.:.:...|:  .|.|                     |.:...:.|:|::..:....
  Fly  2125 ------LFCGSLSNNVVS--LDCG---------------------HVSRTAEDFYTVRCQVADMR 2160

  Fly  1332 SVKEALEILVGRDQLEG---VTGSKTKQEVVAWQQMTLEKLPVVLILHLKYFDYRSDGCTKILKK 1393
            :::|:|:.:..:|.|||   .|.|:..::|.|.::...:|||.:|..:...:.:..  .|.:.:|
  Fly  2161 NLQESLDEVTVKDTLEGDNMYTCSQCGKKVRAEKRACFKKLPQILCFNTMRYTFNM--VTMLKEK 2223

  Fly  1394 VD----FPVELK----IDAKILGSKKTSQKQR--------------------------------A 1418
            |:    ||:.|.    ::..::..:...:::|                                .
  Fly  2224 VNTHFSFPLRLNMCHYVEKTLMPQQYKEERERRQKEKEGADGSGDGNDNEKAEATLDDDIEECYE 2288

  Fly  1419 YRLFAVVYHDGKEASKGHYITDV-------FHTGYSSWLRYDDSSVKP----------------- 1459
            |.|..|..|.| .|..|||.:.:       :|| :..|..::|:.|||
  Fly  2289 YELVGVTVHTG-TADGGHYYSFIKERTKTSYHT-HERWFLFNDAEVKPFDPSQIAAECFGGEMTS 2351

  Fly  1460 -----VSEKHV-LQPHTPRVPYLLYYRRSDTLPPQQQQTQQQ 1495
                 |:||:: .........|:|:|.|  .||...|:...:
  Fly  2352 KTYDSVTEKYLDFSFEKTNSAYMLFYER--RLPEHLQRRHSE 2391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_001261229.1	UCH	1109..1479	CDD:278850	78/462 (17%)
		Peptidase_C19	1223..1480	CDD:239072	57/329 (17%)
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	79/450 (18%)
		UCH	2014..2377	CDD:278850	77/442 (17%)
		DUF3517	2723..>2877	CDD:288853

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D625455at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920