DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp10 and not

DIOPT Version :9

Sequence 1:	NP_001261229.1	Gene:	Usp10 / 38103	FlyBaseID:	FBgn0052479	Length:	1517	Species:	Drosophila melanogaster
Sequence 2:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	106/446 - (23%)
Similarity:	172/446 - (38%)	Gaps:	146/446 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1096 TRHKTNLASIS-----LRP------RGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLS 1149
            |..:|||...:     :||      |||.|....|::|.|:|||
  Fly   133 TTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQAL--------------------- 176

  Fly  1150 EVKTPTVNAMMSFMTNFSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDMA--FE-------- 1204
             |.||.::..  ||:             :..:.||:|..|      .|.|:::  |:
  Fly   177 -VHTPLLSDY--FMS-------------DRHDCGSKSSHK------CLVCEVSRLFQEFYSGSRS 219

  Fly  1205 PTEIYKL----WNDSREEHVEG-RQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAEP 1264
            |..:::|    ||.::  |:.| .|:||.||....|:.|:...::.               .||.
  Fly   220 PLSLHRLLHLIWNHAK--HLAGYEQQDAHEFFIATLDVLHRHCVKA---------------KAEH 267

  Fly  1265 EDGGDVWQMICNNRNKGSVTRQTD------FGRTP--VSDIFRGELRSRLQREGEHSTDVI---- 1317
            |...       |:...||.|..::      :|:..  :..||.|.|:|          ||:
  Fly   268 ESKS-------NSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQS----------DVVCQAC 315

  Fly  1318 -------QPFFTLQLNIEK-----AASVKEALEILVGRDQLEGVTGS---------KTKQEVVAW 1361
                   .||:.:.|::.:     ..:.|..::.|....:.|.: ||         |:.||  :.
  Fly   316 NGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHL-GSAAKIKCSTCKSYQE--ST 377

  Fly  1362 QQMTLEKLPVVLILHLKYFDYRSDGCTKILKKVDFPVELKIDAKILGSKKTSQKQRAYRLFAVVY 1426
            :|.:|..||.|:..|||.|::.:....||...:.||||..: ...:..||.:.....:.|:|||.
  Fly   378 KQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDM-TPFMSEKKNAYGDFRFSLYAVVN 441

  Fly  1427 HDGKEASKGHYITDVFHTGYSSWLRYDDSSVKPVSEKHVLQPHTPRVPYLLYYRRS 1482
            |.| ....|||...|.|. ..:|::.||..:...|.|.||...    .|||:|.::
  Fly   442 HVG-TIDTGHYTAYVRHQ-KDTWVKCDDHVITMASLKQVLDSE----GYLLFYHKN 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_001261229.1	UCH	1109..1479	CDD:278850	100/423 (24%)
Usp10	NP_001261229.1	Peptidase_C19	1223..1480	CDD:239072	71/289 (25%)
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	99/417 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456866
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840