Protein Alignment Usp10 and USP27X

DIOPT Version :9

• Sequence 1: NP_001261229.1
• Gene: Usp10 / 38103
• FlyBaseID: FBgn0052479
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_001138545.1
• Gene: USP27X / 389856
• HGNCID: 13486
• Length: 438
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 107/447 - (23%)
• Similarity: 166/447 - (37%)
• Gaps: 124/447 - (27%)

  Fly  1097 RHKTNLASISLRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVKTPTVNAMMS 1161
            |.:...:|.::..|||.|..|.|::|.|:|||.. :|   :||..........|:.:|.    :.
Human    65 RRRRITSSFTIGLRGLINLGNTCFMNCIVQALTH-TP---ILRDFFLSDRHRCEMPSPE----LC 121

  Fly  1162 FMTNFSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDMAFEPTEIYKL----WNDSREEHVEG 1222
            .:...|||       ...|..|:.|                  |...|||    |..:|  |:.|
Human   122 LVCEMSSL-------FRELYSGNPS------------------PHVPYKLLHLVWIHAR--HLAG 159

  Fly  1223 -RQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAEPEDGGDVWQMICNNRNKGSVTRQ 1286
             ||:||.|||...|                                 ||....|...:.|.....
Human   160 YRQQDAHEFLIAAL---------------------------------DVLHRHCKGDDVGKAANN 191

  Fly  1287 TDFGRTPVSDIFRGELRSRLQREGEHS-TDVIQPFFTLQLNIEKAAS----VKEALEILV-GRDQ 1345
            .:.....:..||.|.|:|.:..:..|. :..|.|.:.:.|::..:.:    :....|..| |...
Human   192 PNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESH 256

  Fly  1346 LEGVT---------------GSKTK---------QEVVAWQQMTLEKLPVVLILHLKYFDYRSDG 1386
            :.|:|               ||..|         ||  :.:|:|:.|||||...|.|.|::.:..
Human   257 IPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQE--STKQLTMNKLPVVACFHFKRFEHSAKQ 319

  Fly  1387 CTKILKKVDFPVELKIDAKILGSKK------------TSQKQRAYRLFAVVYHDGKEASKGHYIT 1439
            ..||...:.||:||.:...:..||:            :...:..|.|||||.|.|...| |||.:
Human   320 RRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLES-GHYTS 383

  Fly  1440 DVFHTGYSSWLRYDDSSVKPVSEKHVLQPHTPRVPYLLYYRRSDTLPPQQQQTQQQN 1496
            .:.| ....|.:.||:.:...|.|.||...    .|||:|.: ..|..:.::.::.|
Human   384 FIRH-HKDQWFKCDDAVITKASIKDVLDSE----GYLLFYHK-QVLEHESEKVKEMN 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_001261229.1	UCH	1109..1479	CDD:278850	102/416 (25%)
		Peptidase_C19	1223..1480	CDD:239072	72/298 (24%)
USP27X	NP_001138545.1	Peptidase_C19D	78..419	CDD:239125	102/416 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910