Protein Alignment Usp10 and USP50

DIOPT Version :9

• Sequence 1: NP_001261229.1
• Gene: Usp10 / 38103
• FlyBaseID: FBgn0052479
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_987090.2
• Gene: USP50 / 373509
• HGNCID: 20079
• Length: 334
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 77/339 - (22%)
• Similarity: 129/339 - (38%)
• Gaps: 72/339 - (21%)

  Fly  1111 GLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVKTPTVNAMMSFMTNFSSLPSGLRL 1175
            ||.|..|.|.:|:|.|.|....|.....        :..:..|...|......|.|:.|.:.:.|
Human    45 GLWNLGNTCCVNAISQCLCSILPLVEYF--------LTGKYITALQNDCSEVATAFAYLMTDMWL 101

  Fly  1176 RLNNLNKGSQSKGKDDFVGSDLQCDMAFEPTEIYKLWN---DSREEHVEGRQEDAEEFLGYVLNK 1237
                        |..|.|..::             .|:   :......:..|:||:|||..|||:
Human   102 ------------GDSDCVSPEI-------------FWSALGNLYPAFTKKMQQDAQEFLICVLNE 141

  Fly  1238 LNDEMLEVIKLIDKPTPQQNGQEPAEPEDGGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGEL 1302
            |:    |.:|       :.:.......|.|..  |..|    :..:|.:|..    ::.:|..:|
Human   142 LH----EALK-------KYHYSRRRSYEKGST--QRCC----RKWITTETSI----ITQLFEEQL 185

  Fly  1303 R-SRLQREGEHSTDVIQPF--FTLQLNIEKAASVKEALEILVGRDQLE-----GVTGSKTKQEVV 1359
            . |.:..:.|..|...:.|  |:|.:..:...|:::.|:....:|.|.     ..:..:||||..
Human   186 NYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETA 250

  Fly  1360 AWQQMTLEKLPVVLILHLKYFDYRSDGCTKILKKVDFPV-ELKIDAKILGSKKTSQKQRAYRLFA 1423
            .  :.::.|.|.::|.|||.||.:.....|:...:.:|: .|.:...|.   ...:|...|.|.|
Human   251 V--RASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYIC---SIFRKYPKYNLCA 310

  Fly  1424 VVYHDGKEASKGHY 1437
            ||.|.| :...|||
Human   311 VVNHFG-DLDGGHY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_001261229.1	UCH	1109..1479	CDD:278850	77/339 (23%)
		Peptidase_C19	1223..1480	CDD:239072	57/224 (25%)
USP50	NP_987090.2	Peptidase_C19R	45..333	CDD:239139	77/339 (23%)
		UCH_1	45..326	CDD:290159	77/339 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910