Protein Alignment Usp10 and Usp16-45

DIOPT Version :10

• Sequence 1: NP_728554.1
• Gene: Usp10 / 38103
• FlyBaseID: FBgn0052479
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Alignment Length: 772
• Identity: 158/772 - (20%)
• Similarity: 233/772 - (30%)
• Gaps: 298/772 - (38%)

  Fly   817 SSPVAWTAPTP--ERKNSQQ---AAAAPAAATASAAPVAITTVTTSTASITA-TPNQFQPETGSS 875
            |.|||...|.|  .||.|.:   .:::.:...::..|...|..|..:.:.|| :|:.|.....::
  Fly   506 SLPVAVEKPQPPQRRKPSPELSLTSSSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFLHAHEAA 570

  Fly   876 SASP--------------AVAAAQQQQPAA-------------------QQHAQAAQTGAAAAPS 907
            |..|              |..||:::|.::                   |..|..|..||....:
  Fly   571 SLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQA 635

  Fly   908 KSHSNYASSKKHQSYEPVVLSSVVATSSSANPQPQLNLAPPAPPASQNSSDSSQLSWASLFASNK 972
            .......:.:...|     .:|.|.||..::...:.||.......|.|:..||.   |||.|.:|
  Fly   636 NDGLEQTNGQTEDS-----TTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSST---ASLTAPSK 692

  Fly   973 PVAKVAPYEASKIAQQQPSHPVLQLAPPQPAQVAAAAPVAQLSSPPQNLPLPTAHQQSQLP--AP 1035
                  .|..|. ...||                   |..:....|:::...:..:.....  |.
  Fly   693 ------TYMDSN-GNAQP-------------------PGEKRDDTPEHMDKDSLEEDENDSGIAT 731

  Fly  1036 VPAPTAPLVTPGALSYSAASAQAVPAPSPASASVKPLKPEPPRPVQQQLDEWTSKYAEYLTRHKT 1100
            .|||||   |..:.|.||.......|.|..|.|...|  |.|
  Fly   732 SPAPTA---TNSSTSTSATGNNNSVAGSGLSGSSGAL--EDP----------------------- 768

  Fly  1101 NLASISLRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVKTPTVNAMMSFMTN 1165
             ||..||...||:.                            |.|:|:.:|.
  Fly   769 -LAPASLVTAGLSE----------------------------KGASVIRQVS------------- 791

  Fly  1166 FSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDMAFEPTEIYKLWNDSREEHVEGRQEDAEEF 1230
                                       ||:                     |:......|||:
  Fly   792 ---------------------------VGA---------------------EQGASNGTEDAD-- 806

  Fly  1231 LGYVLNKLNDEMLEVIKLIDKP--TPQQNGQEPAEPEDGGDVWQMICNNRNKGSVTRQTDFGRTP 1293
                         ...|.|::|  ||.| .|..|:.:           .|.|...|:......|.
  Fly   807 -------------GEAKAIEQPEKTPSQ-AQAMAQAQ-----------ARTKRVRTQSYSDWSTT 846

  Fly  1294 VSDIFRGELRSRLQREGEHSTDVIQPFFTLQLNIEKAASVKEALEILVGRDQL------EGVTGS 1352
            ::..::.|       :||.|.......||             |:|::.|::::      :.:.||
  Fly   847 IAPRYQCE-------DGECSVQSCLNNFT-------------AVELMTGQNKVGCDSCTQRINGS 891

  Fly  1353 KTKQEVV---AWQQMTLEKLPVVLILHLKYFDYRSDGC--TKILKKVDFPVELKIDAKILGSK-- 1410
            ..|.:.|   |.:|:.:...|.|||||||.|.. ...|  .|:.:.|.:|..|.| |...|||
  Fly   892 DPKAKSVNTNATKQLLVSSPPAVLILHLKRFQL-GPRCIFRKLTRPVSYPNLLDI-AAFCGSKVK 954

  Fly  1411 -----KTSQKQRAYRLFAVVYHDGKEASKGHYITDV-----FHTGYSSW----------LRYDDS 1455
                 ...||:..|.|:.||.|.|.... |||...|     ...|...|          |..||.
  Fly   955 NLPNIDRKQKKLLYALYGVVEHSGGMYG-GHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDD 1018

  Fly  1456 SVKPVSEKHVLQPHTPRVPYLLYYRRSD------------------TLPPQQQQTQQ 1494
            .:|.:.|  :|.....|..:|.....||                  ..|.::|||||
  Fly  1019 QLKKLEE--LLAKEKAREQHLKVLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQ 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_728554.1	UCH	1110..1479	CDD:425685	80/403 (20%)
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464
		UBP12	<307..990	CDD:227847	139/685 (20%)
		Peptidase_C19	307..>512	CDD:470612	4/5 (80%)
		Peptidase_C19K	<849..1123	CDD:239132	64/250 (26%)