Protein Alignment CG12502 and Tmem200c

DIOPT Version :10

• Sequence 1: NP_612067.2
• Gene: CG12502 / 38102
• FlyBaseID: FBgn0035171
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001238855.1
• Gene: Tmem200c / 501201
• RGDID: 1561734
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 741
• Identity: 147/741 - (19%)
• Similarity: 218/741 - (29%)
• Gaps: 285/741 - (38%)

  Fly    12 KRKHSLGNLRRAHPASGATWNVQVVRGKMSSKCLWHACRALILGLTLMLLGAGMATLGYYADHLS 76
            |||......|:.        :|.||:||: ..|......|| .|:.::|:|..||.:||:.
  Rat    26 KRKRKAKKRRKN--------DVVVVKGKL-KLCSISGLIAL-CGILVLLVGIAMAVVGYWP---- 76

  Fly    77 MGSELRGNVTVRVKNDLKGFHLNNFAYVGPIVMGFGG---FIVVASCVMTFEARDSAAKVVPARL 138
                 :.|...|                       ||   |:.|.|...|..|.:|::
  Rat    77 -----KANAANR-----------------------GGSKQFLPVGSIHRTGAASNSSS------- 106

  Fly   139 RAGGGGSSKNPSRSNQGSSASQRRGMGAQYQSSRWDQHFGVFRSSPGDPHQQPQTACISTTHPHQ 203
                  .:|||::::.|:..                   ||..||.|.|...|.....:|:....
  Rat   107 ------GNKNPAKNHSGTPG-------------------GVNSSSVGGPRSSPPARTAATSSSSS 146

  Fly   204 HSHPQQPFDREALTAELVQFSRSLSASNRFCPQWRRLSGAGSAPDLSGSHAHANTTN-------- 260
            .|                  |.|.|.|..|.  :|..||          :.|::...
  Rat   147 SS------------------SSSSSTSVGFF--FRIFSG----------YLHSDKLKVFGPLIMG 181

  Fly   261 -------STNATNHQN---PTTTVTTN--YYNLLSLNRLSPLDWELYCSHRRHRRHHHRHSHHHH 313
                   ..||..|:|   .|..:...  |..::.::.|...|.....:......
  Rat   182 IGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDVHSLRAKDLAAAAAAAAAAA---------- 236

  Fly   314 HHHHKSSSSSVRRVRP-------------------VRPGLGAGS----------------QPSG- 342
                .|||::.....|                   ::||..|||                .|:|
  Rat   237 ----ASSSAAAPGSAPPGAAPLNGFLNYVQSRGLELKPGSCAGSADAFGAAAMLARGSWPHPAGL 297

  Fly   343 GGGGGGGGGAGS----SSSARIISNSSSLIQ------------RATRECSLLQPPAASRVYWQAS 391
            ||||.|...|||    :||.|......||.:            ...|..::....||:.....|:
  Rat   298 GGGGSGTREAGSPPDLASSPRCPREPPSLTEAVYSIYRERSSGAGRRRTTVAAVAAATATVTAAA 362

  Fly   392 SFDGGSNHPP-----------------GLGMSSGA----EKRSERNKRSDTAKRHVLSRQRPIEQ 435
            |  |||:..|                 |..:|:.|    ....:|::.|:.|.   .|..||..:
  Rat   363 S--GGSSPAPCSPTGSWGRQSTASSLVGSSLSAFALLPLHGDRDRDRDSEGAS---CSWHRPPGE 422

  Fly   436 EEARDHSRSPLGHRRNSTMSD---SSYSGRW--------------------------TARCASMA 471
            ..:||..|..|    :.:::|   :....||                          |.|.|:..
  Rat   423 RGSRDLPRGEL----DLSLTDLRGAEGGARWASGEPEEPEGGTTACTARGQGRRLPRTGRYAAWR 483

  Fly   472 SR-TSSIESRRVQVDLHSPEVMPKSILRSPKRYSSGPSATPSVEKEFRSQLSVCSEPPPPVRQLS 535
            .| ||.:...|..   .|||..|............|..||||        |.:..|..|.||:.|
  Rat   484 RRSTSGLPEYRAP---PSPEPPPSGFAADLDSGPPGTVATPS--------LPLRPEDSPGVRRDS 537

  Fly   536 GQSSMEPAVPEESLDQSEEQEETTQPKASYEEITELQHHTSSLPPKKAR------PGFLPLARSE 594
            ..|            ||::|..:.:   .|..:.|......|:....||      ....|.....
  Rat   538 HSS------------QSDDQSSSNK---GYTPLREADTSVESVVDVVARKRLDCEAATDPSTEHS 587

  Fly   595 QEEDPRPVANPLYRSNSSRQFYRPKK 620
            ..|.|.|....:......|||...:|
  Rat   588 SPEGPSPEPTRVELHTGQRQFTNKEK 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12502	NP_612067.2	PTZ00449	<395..>618	CDD:185628	58/279 (21%)
Tmem200c	NP_001238855.1	DUF2371	14..208	CDD:462979	56/285 (20%)