Protein Alignment dpr20 and KIRREL3

DIOPT Version :9

• Sequence 1: NP_612066.1
• Gene: dpr20 / 38101
• FlyBaseID: FBgn0035170
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_011541328.1
• Gene: KIRREL3 / 84623
• HGNCID: 23204
• Length: 809
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 102/533 - (19%)
• Similarity: 178/533 - (33%)
• Gaps: 143/533 - (26%)

  Fly    34 CAVPNLIRLLLLI--ATIMGSG-----------------------LVQAKTIYDSVNMIQSLDAL 73
            ||:|.....:|.|  ...:|.|                       :::|:...|:|...|::.|.
Human    75 CAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAA 139

  Fly    74 VEPRETTKVPLQTTPATPPTAHAHIHNQVSTLRSSYEDSDDGVDGDYVIPESQT---------ST 129
            :..|     |.:.|...||.....:...|.:||:          ||   |.:.|         ::
Human   140 IRSR-----PARLTVLVPPDDPVILGGPVISLRA----------GD---PLNLTCHADNAKPAAS 186

  Fly   130 VAILDQDSSMKGQDMESLSLQAGSGTVSPKSSPDSSGHKKNASFQQIGSQNVNALVPA---TVAT 191
            :..|.:...:.|.......|:.|.......:...|.|..:|.  |.|..:..|..:|.   |..|
Human   187 IIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENG--QSIVCRATNKAIPGGKETSVT 249

  Fly   192 TSSGLPSSSNASL---------------ATPTEPARNRSTGLVRNSAVK----------VDSKHP 231
            .....|...|.|:               :....||..:.....|...:|          ||..:
Human   250 IDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTY- 313

  Fly   232 LSKGQKTDAPMLNYIFDTFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRISLL 296
                  ...|:...:.:...|.|.....|..:||....     :..:|.|..||....:|..:..
Human   314 ------FSEPVSCEVTNALGSTNLSRTVDVYFGPRMTT-----EPQSLLVDLGSDAIFSCAWTGN 367

  Fly   297 QDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYE 361
            ...|:.|::       :.:|..|.                      |...|.:.:|:::|...|.
Human   368 PSLTIVWMK-------RGSGVVLS----------------------NEKTLTLKSVRQEDAGKYV 403

  Fly   362 CQISTHPPRV----IQINLHVNAPKVMIVDEVGDPLQ-EKYYEIDSTLQLSCVVRNVAMTSSVVF 421
            |:...  |||    .::.|.||.|.::...:....|. ||.       |:.|.:|:......:.
Human   404 CRAVV--PRVGAGEREVTLTVNGPPIISSTQTQHALHGEKG-------QIKCFIRSTPPPDRIA- 458

  Fly   422 WKHMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKTDSGN-YTCSI-SEFQNFTIVVHILN 484
            |...:|:|. ..|.|..:|:|...|:|..|||:|:.|.:.|... |.|:. :.|.:.|.::.:
Human   459 WSWKENVLE-SGTSGRYTVETISTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRL-- 520

  Fly   485 GESFAELHHGGAV 497
            .|..:|:..|..:
Human   521 KEQGSEMKSGAGL 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	15/86 (17%)
		Ig	279..378	CDD:299845	19/102 (19%)
		Ig	400..471	CDD:299845	20/72 (28%)
		IG_like	402..480	CDD:214653	22/79 (28%)
KIRREL3	XP_011541328.1	Ig	58..149	CDD:299845	14/78 (18%)
		IG_like	60..149	CDD:214653	14/78 (18%)
		I-set	156..249	CDD:254352	19/107 (18%)
		Ig2_KIRREL3-like	171..252	CDD:143236	15/82 (18%)
		Ig_2	260..337	CDD:290606	10/83 (12%)
		I-set	341..422	CDD:254352	20/116 (17%)
		IGc2	355..406	CDD:197706	13/79 (16%)
		Ig5_KIRREL3	424..521	CDD:143306	26/107 (24%)
		IG_like	432..521	CDD:214653	25/99 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810