DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and KIRREL2

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_954649.3	Gene:	KIRREL2 / 84063	HGNCID:	18816	Length:	708	Species:	Homo sapiens

Alignment Length:	213	Identity:	54/213 - (25%)
Similarity:	78/213 - (36%)	Gaps:	41/213 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 PHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTY 329
            |||     :.|..:|.|..|....|.|.:..... .|.|.:         :|.||.    |....
Human    24 PHF-----LQQPEDLVVLLGEEARLPCALGAYWG-LVQWTK---------SGLALG----GQRDL 69

  Fly   330 TGDKRYKMEFQYPNNWR-LKITNVKKDDEAIYECQISTHPPRVIQINLHV----NAPKVMIVDEV 389
            .|..||.:.....|... |.|..|:.:|||.||||.:....|.....|||    .||:|:
Human    70 PGWSRYWISGNAANGQHDLHIRPVELEDEASYECQATQAGLRSRPAQLHVLVPPEAPQVL----- 129

  Fly   390 GDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDG----AN 450
            |.|.......:.:  .|:|..|..|..:..:.| ..|.:|     ..|.:....|:::|    ..
Human   130 GGPSVSLVAGVPA--NLTCRSRGDARPTPELLW-FRDGVL-----LDGATFHQTLLKEGTPGSVE 186

  Fly   451 STLSIAKISKTDSGNYTC 468
            |||::...|..|...:.|
Human   187 STLTLTPFSHDDGATFVC 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	25/87 (29%)
		Ig	279..378	CDD:299845	27/99 (27%)
		Ig	400..471	CDD:299845	16/73 (22%)
		IG_like	402..480	CDD:214653	16/71 (23%)
KIRREL2	NP_954649.3	IG_like	30..119	CDD:214653	27/102 (26%)
		IGc2	38..106	CDD:197706	23/81 (28%)
		I-set	126..224	CDD:254352	20/92 (22%)
		Ig2_KIRREL3-like	141..223	CDD:143236	16/72 (22%)
		Cell attachment site. /evidence=ECO:0000255	149..151		1/1 (100%)
		Ig	231..306	CDD:299845
		IG_like	234..308	CDD:214653
		Ig	312..395	CDD:299845
		I-set	317..395	CDD:254352
		Ig	397..501	CDD:299845
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	545..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810