DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and aebp1b

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio

Alignment Length:	467	Identity:	91/467 - (19%)
Similarity:	157/467 - (33%)	Gaps:	146/467 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LVQAKTI--YDSVNMIQSLDALVEPRETTKVPLQTTPATPPTAHAH----IHNQVSTLRS----S 108
            |:|.|.|  |.::.:.|....|.:.....|.....:|........|    :||..|.|.|    :
Zfish    55 LLQVKIIPPYATIEVGQHKQLLCKVSSDAKNINWVSPNGEKVLTKHGNLKVHNHGSVLSSLTVLN 119

  Fly   109 YEDSDDGV------DGDYVIPESQTSTVAI------LDQDSSMKGQDME------SLSLQAGSGT 155
            ...::.|:      :||   .||| :||.:      :.:|:..||::..      |...:|...|
Zfish   120 ANLNNAGIYKCVATNGD---TESQ-ATVKLDIILKRMRRDTDRKGREKRLKEPKPSKKPKASKPT 180

  Fly   156 VSPKSSPDSSGHKKNASFQQIGSQNVNALVPATVATTSS-------------------GLPSSSN 201
            ..|||.....|.|......:...:....:...|||.|::                   ..|:.:.
Zfish   181 KKPKSEKKGKGEKGGKKKGKKNREESTTVATTTVAPTTTVPMEYEEFYDPEPDQYWDEDFPAETT 245

  Fly   202 A---SLATPTEPARNRSTGLVRNSAV-------KVDSKHPLSK---GQKTDAPMLNYIFDTFSSA 253
            .   :..||||..::....:...|..       |||...|.:.   |:..|
Zfish   246 TVARTTTTPTEKTKDFIPDMDEYSQPDSYDDYWKVDEPTPTTSVIAGRPAD-------------- 296

  Fly   254 NKHHHHDQRYGPHFEDVQRIGQATNLTVQAG---SSIHLNCRISLLQDKTVSWVRHNTQDEGKDN 315
                  |..|.    |.:.:....||....|   ||...:.:.:..::.||....::..:|
Zfish   297 ------DDDYW----DARSVEMVENLPFPDGKEISSTDNDWQYTTTEEPTVPPFENSWYEE---- 347

  Fly   316 GNALDLLTVGMHTYTGDKRYKMEFQYPNNWRLKITNVKKD-------DEAIYECQISTHPPRVIQ 373
                       :.|..:|:.:.|.:     ||:....:|:       :|...|.:|...||||.:
Zfish   348 -----------YEYGHEKKLEEERE-----RLRKEQEEKEREERKRLEEEERERRIYRPPPRVYR 396

  Fly   374 INLHVNAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGV 438
                  .||:.      .||..:.:.||:. ||        :||||  ::|     .|...|..:
Zfish   397 ------EPKIC------PPLGMESHRIDND-QL--------LTSSV--FQH-----RYGSHRARL 433

  Fly   439 SVKTELMEDGAN 450
            :::....:|..|
Zfish   434 NIQASGDDDDMN 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	16/96 (17%)
		Ig	279..378	CDD:299845	20/108 (19%)
		Ig	400..471	CDD:299845	13/51 (25%)
		IG_like	402..480	CDD:214653	11/49 (22%)
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	22/94 (23%)
		IG_like	62..145	CDD:214653	19/86 (22%)
		FA58C	402..555	CDD:238014	15/60 (25%)
		FA58C	403..556	CDD:214572	15/59 (25%)
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900