DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and lrit3a

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001122166.1	Gene:	lrit3a / 558559	ZFINID:	ZDB-GENE-080723-63	Length:	636	Species:	Danio rerio

Alignment Length:	183	Identity:	45/183 - (24%)
Similarity:	72/183 - (39%)	Gaps:	23/183 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 YDSVNMIQSLDAL-VEPRETTKVPLQTTPATPPTAHAHI-HNQVSTLRSSYEDSDDGVDGDYVIP 123
            ::|:..:.||..| :.....|.||::..|......:..| .|:::||.|...|......|  :.|
Zfish   122 WESLKEMPSLKTLDLHNNRLTSVPVEAAPYLINITYLDISSNKLTTLPSDLVDIWPPFSG--IQP 184

  Fly   124 ESQTSTVAILD-QDS----SMKGQDMESLSLQAGSGTVSPKSSPDSSG--HKKNASFQQIGSQNV 181
            .:.||...:|. ||:    ..:...:..||..||...|........||  |.....||:   ..:
Zfish   185 SANTSQKTVLGLQDNPWYCDCRISKLIELSKMAGIPVVLMDQVLTCSGPEHLSGVLFQR---AEL 246

  Fly   182 NALVPATVATTSSGL--PSSSNASL-------ATPTEPARNRSTGLVRNSAVK 225
            :..|..||.|:::.:  |..||..|       .|||.........:|.|:.|:
Zfish   247 DQCVKPTVMTSATKITSPLGSNVLLRCDANGFPTPTLLWTTADGSVVNNTVVQ 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653
		Ig	279..378	CDD:299845
		Ig	400..471	CDD:299845
		IG_like	402..480	CDD:214653
lrit3a	NP_001122166.1	LRR_8	81..141	CDD:290566	4/18 (22%)
		leucine-rich repeat	83..106	CDD:275378
		LRR_4	107..145	CDD:289563	5/22 (23%)
		leucine-rich repeat	107..130	CDD:275378	1/7 (14%)
		LRR_8	129..>171	CDD:290566	11/41 (27%)
		LRR_4	129..170	CDD:289563	11/40 (28%)
		leucine-rich repeat	131..154	CDD:275378	6/22 (27%)
		leucine-rich repeat	155..168	CDD:275378	2/12 (17%)
		TPKR_C2	199..249	CDD:301599	10/52 (19%)
		Ig	252..343	CDD:299845	13/48 (27%)
		IG_like	261..343	CDD:214653	10/39 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900