DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and igsf9a

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_005155702.1	Gene:	igsf9a / 557459	ZFINID:	ZDB-GENE-060503-288	Length:	1619	Species:	Danio rerio

Alignment Length:	333	Identity:	63/333 - (18%)
Similarity:	102/333 - (30%)	Gaps:	144/333 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   241 PMLNYI------FDTFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRI------ 293
            |:|..|      |:..|:|.:|                      :..:..||..|.|.:
Zfish     7 PLLEVIVAVLCLFNDTSAAEEH----------------------VRAKKDSSAVLPCSLPAPQKD 49

  Fly   294 SLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMH-----TYTGDKRYKMEFQYPNNWRLKITNVK 353
            |......:.|||     :|.|....:.|   |:|     .|.|      .........|:::.::
Zfish    50 SSASQYVIEWVR-----QGFDTPIFMQL---GVHPRVHPDYDG------RVSLFGGTSLQMSGLQ 100

  Fly   354 KDDEAIYECQI----------------------------STHPPRV---------IQINLHVNAP 381
            .:||..|||:|                            .|.||.|         ::.....|..
Zfish   101 LEDEGWYECRILPLDQTTEEAGSSGSWTRLSVTAPPVLTETSPPEVEVFVGRSLTLKCAAQGNPR 165

  Fly   382 KVMIVDEVGDPL--QEKYYEIDSTLQLSCVVRNVA-----MTSS-----------------VVFW 422
            ..:...:.|.|:  |.|...::.::....|.|..|     .||:                 |:..
Zfish   166 PTITWSKDGAPIKPQHKVKMVNGSVSFHAVSREAAGQYQCYTSNSEGNATHVTRLKIIGPPVIII 230

  Fly   423 KHMDNILN-------------------YDVTRGGVSV--------KTELMEDGANSTLSIAKISK 460
            ...|.:||                   |...|.||.:        :.:::.||   ||.|::::.
Zfish   231 PPSDTVLNMSQDAKLKCQAEADPPNMTYVWQRQGVDIYHIDSLKSRIKVIVDG---TLLISRLAP 292

  Fly   461 TDSGNYTC 468
            .|||||||
Zfish   293 EDSGNYTC 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	22/125 (18%)
		Ig	279..378	CDD:299845	26/146 (18%)
		Ig	400..471	CDD:299845	25/118 (21%)
		IG_like	402..480	CDD:214653	25/116 (22%)
igsf9a	XP_005155702.1	IG_like	27..110	CDD:214653	21/118 (18%)
		Ig	35..111	CDD:299845	21/89 (24%)
		I-set	140..221	CDD:254352	14/80 (18%)
		IGc2	151..212	CDD:197706	10/60 (17%)
		Ig	233..318	CDD:299845	19/71 (27%)
		I-set	233..318	CDD:254352	19/71 (27%)
		Ig	<349..402	CDD:299845
		IG_like	423..502	CDD:214653
		Ig	435..498	CDD:143165
		FN3	507..602	CDD:238020
		fn3	614..696	CDD:278470
		PHA02666	1105..>1312	CDD:222914
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900