DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr20 and OPCML

DIOPT Version :9

Sequence 1:NP_612066.1 Gene:dpr20 / 38101 FlyBaseID:FBgn0035170 Length:525 Species:Drosophila melanogaster
Sequence 2:NP_001306032.1 Gene:OPCML / 4978 HGNCID:8143 Length:354 Species:Homo sapiens


Alignment Length:214 Identity:55/214 - (25%)
Similarity:85/214 - (39%) Gaps:58/214 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   272 RIGQAT------NLTVQAGSSIHLNCRISLLQDKT--VSWVRHNTQDEGKDNGNALDLLTVGMHT 328
            |.|.||      |:||:.|.|..|.|.|   .|:.  |:|:..:|            :|..|...
Human    32 RSGDATFPKAMDNVTVRQGESATLRCTI---DDRVTRVAWLNRST------------ILYAGNDK 81

  Fly   329 YTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYECQIST-HPPRVIQINLHVNAPKVMI------- 385
            ::.|.|..:....|..:.:.|.||...||..|.|.:.| :.|:..:::|.|..|..::       
Human    82 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDIT 146

  Fly   386 VDEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGAN 450
            |:|            .|::.|.|:.  :......|.|:|    |:....:|.||      ||   
Human   147 VNE------------GSSVTLLCLA--IGRPEPTVTWRH----LSVKEGQGFVS------ED--- 184

  Fly   451 STLSIAKISKTDSGNYTCS 469
            ..|.|:.|.:..||.|.||
Human   185 EYLEISDIKRDQSGEYECS 203

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr20NP_612066.1 IG_like 278..365 CDD:214653 24/88 (27%)
Ig 279..378 CDD:299845 26/101 (26%)
Ig 400..471 CDD:299845 20/70 (29%)
IG_like 402..480 CDD:214653 20/68 (29%)
OPCMLNP_001306032.1 Ig 44..132 CDD:416386 27/102 (26%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 2/6 (33%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 3/23 (13%)
Ig strand C' 72..76 CDD:409353 1/15 (7%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 10/33 (30%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 2/8 (25%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 135..206 CDD:404760 23/96 (24%)
Ig strand A 135..138 CDD:409353 1/2 (50%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 3/10 (30%)
Ig strand C 165..170 CDD:409353 1/4 (25%)
Ig strand C' 171..174 CDD:409353 2/6 (33%)
Ig strand F 198..206 CDD:409353 4/6 (67%)
Ig 224..312 CDD:416386
putative Ig strand A 224..230 CDD:409353
Ig strand B 240..244 CDD:409353
Ig strand C 253..257 CDD:409353
Ig strand E 279..283 CDD:409353
Ig strand F 293..298 CDD:409353
Ig strand G 306..309 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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