DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and negr1

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_009300786.1	Gene:	negr1 / 445374	ZFINID:	ZDB-GENE-040822-27	Length:	360	Species:	Danio rerio

Alignment Length:	345	Identity:	69/345 - (20%)
Similarity:	113/345 - (32%)	Gaps:	111/345 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 IGSQNVNALVPATVATTSSGLPSSSNASLATPTEP--ARNRSTGLVR--------------NSAV 224
            :..|.:.|::.:......|.||:.......|.:|.  :|...|.|:|              .|::
Zfish    12 VSGQWLTAIILSLCCFLPSCLPAGQTVDYTTSSESVVSRQGDTALLRCYLLDGISKGAWLNRSSI 76

  Fly   225 ------------------KVDSKHPLS----KGQKTDAPMLNYIFDTFSSANKHHHHDQ---RYG 264
                              .|..||..|    |...||..:  |.....|..|.|....|   :..
Zfish    77 IYAGNDKWSGDPRVSIVSNVGDKHEYSLQIQKVDVTDEGV--YTCSIQSERNLHPKLIQLIVKVP 139

  Fly   265 PHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTY 329
            |...|:     ::::||..||::.|.|..|...:..:|| ||.:....|
Zfish   140 PKIYDI-----SSDITVNEGSNVSLICAASGKPEPKISW-RHISPSARK---------------- 182

  Fly   330 TGDKRYKMEFQYPNNWRLKITNVKKDDEAIYEC----QISTHPPRVIQINLHVNAPKVMIVDEVG 390
                       |.:...|.||.:.:|....|||    .|::...:.:::.  ||.|..:
Zfish   183 -----------YESGEYLNITGISRDQAGDYECGAENDIASPDTKTVRVT--VNFPPAI------ 228

  Fly   391 DPLQEKYYEIDS-------TLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDG 448
                   :|:.|       ...|.|  ...|:.|.|..|...:..:|    .|...|...|   .
Zfish   229 -------HEMKSHGVRPGQVALLRC--EAAAVPSPVFEWYKGEKRIN----MGQGIVINNL---S 277

  Fly   449 ANSTLSIAKISKTDSGNYTC 468
            :.|.|::..:::...|||||
Zfish   278 SRSVLTVKNMTQDRYGNYTC 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	20/90 (22%)
		Ig	279..378	CDD:299845	21/102 (21%)
		Ig	400..471	CDD:299845	18/76 (24%)
		IG_like	402..480	CDD:214653	18/74 (24%)
negr1	XP_009300786.1	Ig	42..121	CDD:299845	15/80 (19%)
		IG_like	44..136	CDD:214653	18/93 (19%)
		I-set	140..222	CDD:254352	23/116 (20%)
		IGc2	153..208	CDD:197706	18/82 (22%)
		IG_like	236..312	CDD:214653	17/71 (24%)
		IGc2	238..304	CDD:197706	17/69 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810