DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and klg

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	62/317 - (19%)
Similarity:	112/317 - (35%)	Gaps:	81/317 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 SQNVNALVPATVATTSSGLPSSSNASLATPTEPARNRSTGLVRNSAVKVD-------SKHPLSKG 235
            |....||.|...|..|    :::|||....:...|||:. |..|..:.:.       ..|..|.|
  Fly     7 SIRTGALAPPITAHAS----ANANASGLRKSSQRRNRAP-LQMNCPILIVISLGWLLHAHAGSGG 66

  Fly   236 QKTDAPMLNYIFDTFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQ--------------AGSS 286
            ...:|.:.|...::.|.:|..              |....|:.||..              .|.:
  Fly    67 FAVEAAISNRGSNSRSMSNVQ--------------QSAVAASTLTATLPRFLSRGHTYRAVVGDT 117

  Fly   287 IHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRYKMEFQYPNNWRLKITN 351
            :.|.|::..|.:..:.|.|            ..::||......|.|:|.::    .:.:.|:|::
  Fly   118 LVLPCQVENLGNFVLLWRR------------GTNVLTASNIMVTRDERVRL----IDGYNLEISD 166

  Fly   352 VKKDDEAIYECQISTHPPRVIQINLH----VNAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRN 412
            ::..|...|.||||   .::.:..:|    :..|.|..:...|.....|    ...:.|.|....
  Fly   167 LEPQDAGDYVCQIS---DKINRDQVHTVEILVPPSVRAIPTSGQLQARK----GGPITLECKGSG 224

  Fly   413 VAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKTDSGNYTCS 469
            ..:.|  ::|          ..:.|.:..|..:.||  ..|::.|:.:..:|.|.|:
  Fly   225 NPVPS--IYW----------TKKSGANKSTARIGDG--PILTLEKLERQQAGVYQCT 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	19/100 (19%)
		Ig	279..378	CDD:299845	22/116 (19%)
		Ig	400..471	CDD:299845	13/70 (19%)
		IG_like	402..480	CDD:214653	13/68 (19%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	13/74 (18%)
		IG_like	109..195	CDD:214653	20/104 (19%)
		Ig	118..191	CDD:143165	19/91 (21%)
		IG_like	205..274	CDD:214653	15/81 (19%)
		IGc2	213..273	CDD:197706	13/69 (19%)
		IGc2	301..367	CDD:197706
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810