DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and dpr5

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	363	Identity:	97/363 - (26%)
Similarity:	155/363 - (42%)	Gaps:	82/363 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 VNALVPATVATTSSGL----PSSSNA-------------------SLATPTEPARNRSTGLVRNS 222
            |.|...:|.||.||.|    .|:|.|                   .|..|.:....||:....:.
  Fly     7 VRATFTSTTATESSPLIGKVISNSRAPQIAHEMLVEYFMALLVIMGLTAPVDKQSRRSSQYFGHL 71

  Fly   223 AVKVDSKHPLSKGQKTDAPMLNYIFDTFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQA--GS 285
            |...:              :.|.|.|.:.:.:          |.|::      .|:..|.|  |:
  Fly    72 AAAEE--------------LSNLIPDNYDAID----------PVFDN------TTDREVIAALGT 106

  Fly   286 SIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRY-KMEFQYPNNWRLKI 349
            :..|:||:..|.|:.|||:|...          |.:||:|:.|||.|:|: .......:.|.|||
  Fly   107 TARLHCRVRHLGDRAVSWIRQRD----------LHILTIGIMTYTNDQRFLARHIDNSDEWVLKI 161

  Fly   350 TNVKKDDEAIYECQISTHPPRVIQINLHVNAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRNVA 414
            .:|::.|..:||||:||.|...:...|.|...|..|:..     :|.:.:..|.:.|:|:.....
  Fly   162 VSVQQRDAGVYECQVSTEPKISLAYKLVVVTSKAQILAN-----RELFIQSGSDINLTCIAPQAP 221

  Fly   415 MTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKTDSGNYTCSISEFQNFTIV 479
            ...:.:.| |.|..|..|..|||:.|::|  :....|.|.|:::..|||||||||.....:.::.
  Fly   222 GPYTHMLW-HKDTELVSDSARGGIRVESE--QQMKTSNLVISRVQHTDSGNYTCSADNSNSDSVF 283

  Fly   480 VHILNGESFAELHHGGAVGWHSTWWNMVMLHAMALLVL 517
            |||:..|..|.:.|  .:|      :.::|..:.||:|
  Fly   284 VHIIKSEQHAAMQH--ELG------SRLLLPPLPLLLL 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	31/89 (35%)
		Ig	279..378	CDD:299845	35/101 (35%)
		Ig	400..471	CDD:299845	25/70 (36%)
		IG_like	402..480	CDD:214653	25/77 (32%)
dpr5	NP_650080.3	V-set	95..191	CDD:284989	36/105 (34%)
		IG_like	98..179	CDD:214653	32/90 (36%)
		IG_like	206..278	CDD:214653	25/74 (34%)
		Ig	211..278	CDD:143165	24/69 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444726
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840