DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and LSAMP

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001305844.1	Gene:	LSAMP / 4045	HGNCID:	6705	Length:	361	Species:	Homo sapiens

Alignment Length:	199	Identity:	47/199 - (23%)
Similarity:	78/199 - (39%)	Gaps:	49/199 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 NLTVQAGSSIHLNCRISLLQDKT--VSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRYKMEFQ 340
            |:||:.|.:..|.|   :::||.  |:|:            |...::..|...::.|.|.::|.:
Human    40 NITVRQGDTAILRC---VVEDKNSKVAWL------------NRSGIIFAGHDKWSLDPRVELEKR 89

  Fly   341 YPNNWRLKITNVKKDDEAIYECQIST-HPPRVIQINLHVNA-PKVMIVDEVGDPLQEKYYEIDST 403
            :...:.|:|..|...||..|.|.:.| |.|:..|:.|.|.. ||:..:..            |.|
Human    90 HSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISS------------DVT 142

  Fly   404 LQLSCVVRNVAMTSS----VVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKTDSG 464
            :.....|..|.|.:.    |:.|:|:              ..|....:|....|.|..|::..||
Human   143 VNEGSNVTLVCMANGRPEPVITWRHL--------------TPTGREFEGEEEYLEILGITREQSG 193

  Fly   465 NYTC 468
            .|.|
Human   194 KYEC 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	22/88 (25%)
		Ig	279..378	CDD:299845	26/101 (26%)
		Ig	400..471	CDD:299845	17/73 (23%)
		IG_like	402..480	CDD:214653	16/71 (23%)
LSAMP	NP_001305844.1	Ig	38..128	CDD:386229	27/102 (26%)
		Ig	132..215	CDD:386229	19/92 (21%)
		Ig_3	219..294	CDD:372822
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810