Protein Alignment dpr20 and IGLON5

DIOPT Version :10

• Sequence 1: NP_612066.1
• Gene: dpr20 / 38101
• FlyBaseID: FBgn0035170
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001094842.1
• Gene: IGLON5 / 402665
• HGNCID: 34550
• Length: 336
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 71/321 - (22%)
• Similarity: 109/321 - (33%)
• Gaps: 113/321 - (35%)

  Fly   276 ATNLTVQAGSSIHLNCRISLLQDK---TVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRYKM 337
            |.|.||..|.:..|:|.|    |:   .|:|:            |..::|..|...:|.|.|.::
Human    39 ADNYTVCEGDNATLSCFI----DEHVTRVAWL------------NRSNILYAGNDRWTSDPRVRL 87

  Fly   338 EFQYPNNWRLKITNVKKDDEAIYECQIST-HPPRVIQINLHVNAPKVMI-------VDE------ 388
            ....|..:.:.||.|...||.:|.|...| |.|...|:.|.|:.|..::       |:|
Human    88 LINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNL 152

  Fly   389 ----VGDP--------LQEKYYEIDSTLQLS-----------CVVRN------------------ 412
                ||.|        |::.:......|::|           ||..|
Human   153 LCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYP 217

  Fly   413 -----------------------VAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLS 454
                                   :|:..:...|...|.:|: ..|..|:.|:||    ...|.|.
Human   218 PTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLS-SGTAEGLKVQTE----RTRSMLL 277

  Fly   455 IAKISKTDSGNYTC-SISEFQNFTIVVHILNG---ESFAELHHG-----GAVGWHSTWWNM 506
            .|.:|....||||| :.:.....:..:.:|..   |:.|....|     .|:||  .||.|
Human   278 FANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPPGLLALLSALGW--LWWRM 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	PHA02785	101..368	CDD:165149	26/95 (27%)
		IG_like	278..365	CDD:214653	24/89 (27%)
		Ig strand B	287..291	CDD:409382	1/3 (33%)
		Ig strand C	300..304	CDD:409382	1/3 (33%)
		Ig strand E	345..349	CDD:409382	0/3 (0%)
		Ig strand F	359..364	CDD:409382	2/4 (50%)
		Ig strand G	371..374	CDD:409382	0/2 (0%)
		IG_like	402..480	CDD:214653	23/130 (18%)
		Ig strand B	404..408	CDD:409353	2/14 (14%)
		Ig strand C	417..423	CDD:409353	0/5 (0%)
		Ig strand E	451..455	CDD:409353	2/3 (67%)
IGLON5	NP_001094842.1	Ig strand G	122..125	CDD:409382	0/2 (0%)
		Ig_3	134..199	CDD:464046	10/64 (16%)
		Ig_3	217..295	CDD:464046	18/82 (22%)
		Ig	41..129	CDD:472250	29/103 (28%)
		Ig strand B	50..54	CDD:409382	1/3 (33%)
		Ig strand C	62..66	CDD:409382	1/3 (33%)
		Ig strand E	95..99	CDD:409382	0/3 (0%)
		Ig strand F	109..114	CDD:409382	2/4 (50%)