DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr20 and Lac

DIOPT Version :9

Sequence 1:NP_612066.1 Gene:dpr20 / 38101 FlyBaseID:FBgn0035170 Length:525 Species:Drosophila melanogaster
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:286 Identity:64/286 - (22%)
Similarity:106/286 - (37%) Gaps:66/286 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   204 LATPTEPA--RNRSTGLVRNS--AVKVDS-----KHPLSKGQKTDAP--MLNYIFDTFSSANKHH 257
            |.|.::|.  ...||.::::|  :::.|.     |..:...|:|||.  ....:..|....:...
  Fly    63 LKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEV 127

  Fly   258 HHDQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLL 322
            ....|..|...|    ....::....||.:.:.|..|.....|::|.|.|         ||  :|
  Fly   128 KLSVRRPPVISD----NSTQSVVASEGSEVQMECYASGYPTPTITWRREN---------NA--IL 177

  Fly   323 TVGMHTYTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYEC----QISTHPPRVIQINLHVNAPKV 383
            .....||.|:             .|:|.:|||:|...|.|    .:|....|  .||:.|....|
  Fly   178 PTDSATYVGN-------------TLRIKSVKKEDRGTYYCVADNGVSKGDRR--NINVEVEFAPV 227

  Fly   384 MIV--DEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMD----NILNYDVTRGGVSVKT 442
            :.|  ..:|..||   |::|    |.|.:.  |.....:.|...|    |..:|.::....:   
  Fly   228 ITVPRPRLGQALQ---YDMD----LECHIE--AYPPPAIVWTKDDIQLANNQHYSISHFATA--- 280

  Fly   443 ELMEDGANSTLSIAKISKTDSGNYTC 468
               ::..:|||.:..:.|...|:|.|
  Fly   281 ---DEYTDSTLRVITVEKRQYGDYVC 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr20NP_612066.1 IG_like 278..365 CDD:214653 22/90 (24%)
Ig 279..378 CDD:299845 26/102 (25%)
Ig 400..471 CDD:299845 15/73 (21%)
IG_like 402..480 CDD:214653 14/71 (20%)
LacNP_523713.2 IG_like 36..131 CDD:214653 13/67 (19%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353 64/286 (22%)
FR2 60..63 CDD:409353 64/286 (22%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 6/30 (20%)
Ig strand D 84..90 CDD:409353 0/5 (0%)
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 1/6 (17%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 24/101 (24%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/16 (6%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/4 (25%)
Ig 227..318 CDD:416386 21/92 (23%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 3/3 (100%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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