DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and DIP-iota

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	244	Identity:	57/244 - (23%)
Similarity:	97/244 - (39%)	Gaps:	38/244 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 TFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGK 313
            :||..|..       .|.|.     |...|.||..|....|.|.:..|....|:|:|.:||
  Fly    22 SFSELNNS-------DPKFS-----GPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQ---- 70

  Fly   314 DNGNALDLLTVGMHTYTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYECQISTHPPRVIQINLHV 378
                  .:|::..|..|.:.|..:.......|:|||.:|::.|...|.|||:|.|.:.....|.|
  Fly    71 ------TILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDV 129

  Fly   379 NAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDN---ILNYDVTRGGVSV 440
            ..|..::..:..   |:........:.|:|....|.|.:  :.|:..:.   :::.|..|...||
  Fly   130 VVPPDIVDYQTS---QDVVRSTGQNVTLTCSATGVPMPT--ITWRREEATPILISDDGDREVFSV 189

  Fly   441 KTELMEDGANSTLSIAKISKTDSGNYTCSISEFQNFTIVVHILNGESFA 489
                  :|.|  |::.::.::..|.|.|..|.....|:...::...:||
  Fly   190 ------EGQN--LTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFA 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	25/86 (29%)
		Ig	279..378	CDD:299845	28/98 (29%)
		Ig	400..471	CDD:299845	15/73 (21%)
		IG_like	402..480	CDD:214653	17/80 (21%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	28/95 (29%)
		Ig	39..122	CDD:299845	28/92 (30%)
		Ig	132..213	CDD:299845	17/93 (18%)
		IG_like	141..227	CDD:214653	18/98 (18%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810