Protein Alignment dpr20 and itgb4

DIOPT Version :9

• Sequence 1: NP_612066.1
• Gene: dpr20 / 38101
• FlyBaseID: FBgn0035170
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_005166847.1
• Gene: itgb4 / 335269
• ZFINID: ZDB-GENE-030131-7209
• Length: 1931
• Species: Danio rerio
• Alignment Length: 626
• Identity: 120/626 - (19%)
• Similarity: 191/626 - (30%)
• Gaps: 215/626 - (34%)

  Fly    14 TKSTTDAT-----KFSSSRGDLHLDCAVPNLIRLLLLIATIMGSGLVQAKTIYDSVNMIQSLDAL 73
            |.||.|.|     .:.|..|||.........|..:.|:......||::.|.:...|     :| |
Zfish  1026 TYSTADLTAKDKKDYISVDGDLSYGAGETEKIVPVKLLELGEQDGLLEDKQVKQFV-----MD-L 1084

  Fly    74 VEPRETTKVPLQTTPATPPTAHAHIHNQVSTLRSSYEDSDDGVDGDYVIPESQT---STVAILDQ 135
            ..||::.|  |...|.|..|......:.|...:.|.: :....|..|.||..:|   .|.|.:..
Zfish  1085 TNPRQSAK--LGRYPRTVITIADKPESSVMAFKKSTQ-TFSTTDSLYTIPVERTGNRETPATVHW 1146

  Fly   136 DSSMKGQ-DMES-LSLQAGSG----TVSPKSSP-------------------------------- 162
            .::...: |:.| |....|..    .::|::.|
Zfish  1147 RTNKASRFDISSPLKFAPGEAEKNILINPRTHPSPIIPEKFNLELLDPSNNAIIGKRKTTEVIVT 1211

  Fly   163 DSSGHKKNASFQQIGSQNVNALVPATVATTSSG----LPSSSNASLATPT------EPARNRSTG 217
            |..|..||..||:        :...|...||.|    .|::..|....|.      :|::|.:..
Zfish  1212 DGRGDGKNQDFQK--------MEYVTQTATSPGGRLYSPANIKAVATGPKNIRLNWKPSQNANGY 1268

  Fly   218 LVR--------NSAVKVDSKHPLSKGQKTDAPMLNYIFDT--FSSANKHHHHDQRYGPHFEDVQR 272
            .|:        :.|..:|.|.|.::....| |..:|....  :::....::.|.......||:.
Zfish  1269 KVKYWIYGDPEDKAKFMDVKTPQAELTNLD-PYCDYEMRVCGYNALGDGNYSDIIQCQTLEDIP- 1331

  Fly   273 IGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKR--- 334
             |:...|.....|.       ::.|   |||.     :..:.||.......:.| ....||:
Zfish  1332 -GEPGRLAFNVISP-------TVTQ---VSWA-----EPAEANGIITGYEVIYM-PINEDKKPTG 1379

  Fly   335 --YKMEFQYPNNWRLKITNVKKDDEAIYECQISTH----PPRVIQINLHVN---------APKVM 384
              .|:....|....|.|.|::......|:.:.|..    |.|...|||...         .|.:.
Zfish  1380 PPKKVMIDNPKKRMLLIENLQPSQTYCYKVRASNKVGWGPYREATINLASQPTRPMSIPIIPDIP 1444

  Fly   385 IVD-EVGDPLQEKYYEIDSTLQLSCVV-------------------------------------- 410
            ||| |.|:       |.||.|..|..|
Zfish  1445 IVDAEAGE-------EYDSYLMYSNEVLRSPTSSLRPSVTDLSDDQFVNGKWEQNFLFPGGGGGS 1502

  Fly   411 --RNVAMTSSVVFWKH---MDNILN------------------YDVTRGGV-------------- 438
              ||::.:|:.  :.|   ..|:.|                  |||..||:
Zfish  1503 LSRNISSSSTT--YSHSTPRTNVTNNSSTTTYISGKGGSTTHRYDVRDGGLLKEDVILRKRSENR 1565

  Fly   439 ----------SVKTELMEDGANSTLSIAKISKTDSGNYTCS 469
                      |:....:..|....|.::..|:|.|.:|:.|
Zfish  1566 HYTEGDGVRDSIVMGNLSGGLLDNLGVSSFSQTTSTSYSLS 1606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	17/91 (19%)
		Ig	279..378	CDD:299845	23/107 (21%)
		Ig	400..471	CDD:299845	24/155 (15%)
		IG_like	402..480	CDD:214653	23/153 (15%)
itgb4	XP_005166847.1	Integrin_beta	37..457	CDD:278776
		EGF_2	<468..490	CDD:285248
		EGF_2	545..573	CDD:285248
		Integrin_B_tail	625..709	CDD:285239
		Calx-beta	991..1064	CDD:295344	11/37 (30%)
		FN3	1242..1326	CDD:238020	14/84 (17%)
		FN3	1331..1420	CDD:238020	19/106 (18%)
		fn3	1640..1720	CDD:278470
		fn3	1751..1835	CDD:278470

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900