DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr20 and Negr1

DIOPT Version :9

Sequence 1:NP_612066.1 Gene:dpr20 / 38101 FlyBaseID:FBgn0035170 Length:525 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:210 Identity:46/210 - (21%)
Similarity:80/210 - (38%) Gaps:56/210 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   278 NLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNG---NALDLLTVGMHTYTGDKRYKMEF 339
            |:.|:.|.:..|.|.:                ::|...|   |...::..|...::.|.|..:..
Mouse    41 NMLVRKGDTAVLRCYL----------------EDGASKGAWLNRSSIIFAGGDKWSVDPRVSIST 89

  Fly   340 QYPNNWRLKITNVKKDDEAIYECQIST-HPPRVIQINLHVNAPKVMIVDEVGDPLQEKYYEIDST 403
            ....::.|:|.||...|:..|.|.:.| |.||.:|::|.|..|             .|.|:|.:.
Mouse    90 LNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVP-------------PKIYDISND 141

  Fly   404 LQLSCVVRNVAMT-------SSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKT 461
            :.:: ...||.:|       ..|:.|:|             :|...:..|:|  ..|.|..|::.
Mouse   142 MTIN-EGTNVTLTCLATGKPEPVISWRH-------------ISPSAKPFENG--QYLDIYGITRD 190

  Fly   462 DSGNYTCSISEFQNF 476
            .:|.|.||.....:|
Mouse   191 QAGEYECSAENDVSF 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr20NP_612066.1 IG_like 278..365 CDD:214653 18/89 (20%)
Ig 279..378 CDD:299845 23/102 (23%)
Ig 400..471 CDD:299845 17/77 (22%)
IG_like 402..480 CDD:214653 17/82 (21%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353 4/13 (31%)
Ig strand A' 40..46 CDD:409353 2/4 (50%)
IG_like 41..129 CDD:214653 24/103 (23%)
Ig strand B 48..56 CDD:409353 2/7 (29%)
CDR1 56..60 CDD:409353 0/19 (0%)
FR2 61..68 CDD:409353 1/6 (17%)
Ig strand C 61..67 CDD:409353 1/5 (20%)
CDR2 69..79 CDD:409353 1/9 (11%)
Ig strand C' 71..74 CDD:409353 0/2 (0%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 9/34 (26%)
Ig strand D 84..91 CDD:409353 1/6 (17%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 2/7 (29%)
CDR3 116..120 CDD:409353 2/3 (67%)
Ig strand G 120..129 CDD:409353 4/8 (50%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A' 139..144 CDD:409353 0/4 (0%)
IGc2 146..204 CDD:197706 16/72 (22%)
Ig strand B 150..157 CDD:409353 2/6 (33%)
Ig strand C 163..168 CDD:409353 2/4 (50%)
Ig strand C' 170..172 CDD:409353 1/1 (100%)
Ig strand E 180..186 CDD:409353 2/5 (40%)
Ig strand F 193..200 CDD:409353 4/6 (67%)
Ig_3 219..295 CDD:404760
putative Ig strand A 219..225 CDD:409353
Ig strand B 235..239 CDD:409353
Ig strand C 248..252 CDD:409353
Ig strand E 274..278 CDD:409353
Ig strand F 288..293 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.