DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and Kirrel1

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_006232737.1	Gene:	Kirrel1 / 310695	RGDID:	727883	Length:	805	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	79/311 - (25%)
Similarity:	118/311 - (37%)	Gaps:	92/311 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 NRSTGLVRNSAVKVDSKHPLSKGQKTDAPML---NYIFDTFSSANKHHHHDQRYGPHFEDVQ-RI 273
            ||||.|:...:..:..| |....||..||.|   ..||.|.:.|             ....| |.
  Rat     5 NRSTCLMTCQSSLLPKK-PRFLSQKMWAPHLVVAYLIFVTLALA-------------LPGTQTRF 55

  Fly   274 GQ-ATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDK---R 334
            .| ..:.||.||....|.| :.|.....|.|.:              |.|.:||.  .|.|   |
  Rat    56 SQEPADQTVVAGHRAVLPC-VLLNYSGIVQWTK--------------DGLALGMG--QGLKAWPR 103

  Fly   335 YKM-----EFQYPNNWRLKITNVKKDDEAIYECQISTHPPRVIQINLHVNAPK--------VMIV 386
            |::     ..||    .|:||:.:..|:|.||||.:....|..:..|.|..|.        .:|:
  Rat   104 YRVVGSADAGQY----NLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVIL 164

  Fly   387 DEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVT-RGGVSVKTELMEDG-A 449
            .:.|.|           ..|:|...|....:::::::        |.| :.|....|||::|| .
  Rat   165 LQAGTP-----------YNLTCRAFNAKPAATIIWFR--------DGTQQEGAVTSTELLKDGKR 210

  Fly   450 NSTLSIAKISKTD---SGNYTC-SISEFQNFTIVVHILNGESFA---ELHH 493
            .:|:|...|..||   ...:|| |::|        .|.||:..:   ::||
  Rat   211 ETTISQLLIQPTDLDIGRVFTCRSMNE--------AIPNGKETSIELDVHH 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	28/94 (30%)
		Ig	279..378	CDD:299845	30/106 (28%)
		Ig	400..471	CDD:299845	19/76 (25%)
		IG_like	402..480	CDD:214653	20/83 (24%)
Kirrel1	XP_006232737.1	I-set	54..148	CDD:254352	32/114 (28%)
		Ig	57..148	CDD:299845	31/111 (28%)
		Ig2_KIRREL3-like	170..251	CDD:143236	24/107 (22%)
		I-set	255..336	CDD:254352
		Ig_2	259..337	CDD:290606
		Ig_2	340..437	CDD:290606
		IG_like	346..437	CDD:214653
		Ig5_KIRREL3	439..536	CDD:143306
		IG_like	451..536	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810