DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and sdk

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	54/281 - (19%)
Similarity:	108/281 - (38%)	Gaps:	61/281 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 SSSNASLATPTEPARNRSTGLVRNSAVKVDSKHP---LSKGQKTDAPMLNYIFDTFSSANKHHHH 259
            :|::..|...|:.|:||...|.:...::|.:.|.   ..||.::.:......| .|:||
  Fly   442 NSASTWLRVKTKTAKNRVKRLAQPRILRVRASHAGLGSEKGSESGSSDRRKEF-RFASA------ 499

  Fly   260 DQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTV 324
                 |..|...:     |:|...|....::||.....:..::|:.:.||        .:|:.:.
  Fly   500 -----PIMELPPQ-----NVTALDGKDATISCRAVGSPNPNITWIYNETQ--------LVDISSR 546

  Fly   325 GMHTYTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYECQISTHPPRVIQINLHVNAPKVMIVDEV 389
            .....:||              |.|:|::..|..:|.| :..:....::...:::   |::..::
  Fly   547 VQILESGD--------------LLISNIRSVDAGLYIC-VRANEAGSVKGEAYLS---VLVRTQI 593

  Fly   390 GDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVS----VKTELMEDGAN 450
            ..|..:....:..|..|.|   .|:...||.:        |.|..|.|.|    ..::.:...|:
  Fly   594 IQPPVDTTVLLGLTATLQC---KVSSDPSVPY--------NIDWYREGQSSTPISNSQRIGVQAD 647

  Fly   451 STLSIAKISKTDSGNYTCSIS 471
            ..|.|..:..:|.|:|.|.::
  Fly   648 GQLEIQAVRASDVGSYACVVT 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	17/86 (20%)
		Ig	279..378	CDD:299845	16/98 (16%)
		Ig	400..471	CDD:299845	18/74 (24%)
		IG_like	402..480	CDD:214653	18/74 (24%)
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845
		IG_like	280..356	CDD:214653
		Ig	280..343	CDD:299845
		IG_like	375..450	CDD:214653	2/7 (29%)
		Ig	378..447	CDD:143165	1/4 (25%)
		Ig	506..587	CDD:299845	17/111 (15%)
		IG_like	506..587	CDD:214653	17/111 (15%)
		I-set	592..682	CDD:254352	19/88 (22%)
		Ig	595..682	CDD:299845	19/85 (22%)
		FN3	686..789	CDD:238020
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810