DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and Igsf9

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001100667.1	Gene:	Igsf9 / 304982	RGDID:	1304566	Length:	1179	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	49/218 - (22%)
Similarity:	87/218 - (39%)	Gaps:	42/218 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 DVQRIGQATNLTVQAGSSIHLNCRISLLQD------KTVSWVRHNTQDEGKDNGNALDL-LTVGM 326
            |.:|..:..::..:||.|..|.|  .||..      ..:.|:|.         |..|.: :..|:
  Rat    19 DGRRKPEVVSVVGRAGESAVLGC--DLLPPAGRPPLHVIEWLRF---------GFLLPIFIQFGL 72

  Fly   327 HTYTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYECQI---STHPPRV-----IQINLHVNAPKV 383
            ::...|..|....:......|:|..::.:|:..|||::   ..|.|..     ..::|.||:|..
  Rat    73 YSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQ 137

  Fly   384 MIVDEVGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDG 448
            .   :...||..:..|::: :.|.||.  :......|.||    ....|:.:|...|:..
  Rat   138 F---QETPPLVLEVKELEA-VTLRCVA--LGSPQPYVTWK----FRGQDLGKGQGQVQVR----- 187

  Fly   449 ANSTLSIAKISKTDSGNYTCSIS 471
             |.||.|.::.:..:|:|||..|
  Rat   188 -NGTLWIRRVERGSAGDYTCQAS 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	20/96 (21%)
		Ig	279..378	CDD:299845	23/113 (20%)
		Ig	400..471	CDD:299845	17/70 (24%)
		IG_like	402..480	CDD:214653	18/70 (26%)
Igsf9	NP_001100667.1	IG	28..110	CDD:214652	20/92 (22%)
		Ig strand A	136..139	CDD:409353	0/5 (0%)
		IG_like	143..223	CDD:214653	21/80 (26%)
		Ig strand A'	145..148	CDD:409353	0/2 (0%)
		Ig strand B	154..161	CDD:409353	3/8 (38%)
		Ig strand C	167..172	CDD:409353	3/8 (38%)
		Ig strand C'	175..177	CDD:409353	0/1 (0%)
		Ig strand D	183..187	CDD:409353	1/3 (33%)
		Ig strand E	189..193	CDD:409353	2/3 (67%)
		Ig strand F	202..210	CDD:409353	5/8 (63%)
		Ig strand G	213..223	CDD:409353
		Ig_3	226..305	CDD:404760
		putative Ig strand A	226..230	CDD:409353
		putative Ig strand A'	235..239	CDD:409353
		putative Ig strand B	241..251	CDD:409353
		putative Ig strand C'	267..270	CDD:409353
		putative Ig strand D	279..282	CDD:409353
		putative Ig strand E	284..290	CDD:409353
		putative Ig strand F	297..305	CDD:409353
		putative Ig strand G	310..319	CDD:409353
		Ig	322..407	CDD:416386
		Ig strand A'	324..328	CDD:409353
		Ig strand B	333..347	CDD:409353
		Ig strand C	353..359	CDD:409353
		Ig strand C'	362..364	CDD:409353
		Ig strand D	371..374	CDD:409353
		Ig strand E	378..382	CDD:409353
		Ig strand F	391..399	CDD:409353
		Ig	418..503	CDD:416386
		Ig strand A	418..421	CDD:409353
		Ig strand A'	427..430	CDD:409353
		Ig strand B	436..443	CDD:409353
		Ig strand C	449..454	CDD:409353
		Ig strand C'	457..459	CDD:409353
		Ig strand D	462..466	CDD:409353
		Ig strand E	469..473	CDD:409353
		Ig strand F	482..490	CDD:409353
		Ig strand G	493..503	CDD:409353
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	766..807
		PHA03247	<777..1062	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..846
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	869..895
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..979
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding. /evidence=ECO:0000250	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900