DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr20 and Lrit1

DIOPT Version :9

Sequence 1:NP_612066.1 Gene:dpr20 / 38101 FlyBaseID:FBgn0035170 Length:525 Species:Drosophila melanogaster
Sequence 2:NP_647547.2 Gene:Lrit1 / 246214 RGDID:628607 Length:623 Species:Rattus norvegicus


Alignment Length:363 Identity:78/363 - (21%)
Similarity:126/363 - (34%) Gaps:126/363 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MRLNEPAARTRPRTKSTTDATKFSSSRGDLHL---------DCAVPNLIRL-------LLLIATI 49
            |||.|....|....|:   ....||.|..|.|         ||.:.:|:.|       |:.|...
  Rat   168 MRLPEELLDTWAHLKT---GPYLSSRRTRLVLGLQDNPWVCDCRLYDLVHLLDGWASNLIFIEAR 229

  Fly    50 M--GSGLVQAKTIYDSVNMIQSLDALVEPRETTKV-PLQTT------------------PATPPT 93
            :  ||....|...:..:.:.:.....:.|..|:.: ||.:|                  .|....
  Rat   230 LRCGSPRSLAGVAFSQLELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRRANGRP 294

  Fly    94 AHAHIHNQVSTLRSSYEDSDDGV-----DGDY-----------------VIPESQTSTVAILDQD 136
            .:..:|.:||:..||:...|..|     .|||                 ::.|.||||     :.
  Rat   295 LNGTVHQEVSSDGSSWTLLDLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTST-----EY 354

  Fly   137 SSMKGQDMESLSLQAGSGTVSPKSSPDSSGHKKNASFQQIGSQNVNALVPATVA-TTSSGLPS-- 198
            :.:.|      :|.|.:|          .|.:..|...::.:::| ..||..|| .|...:||  
  Rat   355 TGIPG------ALWARTG----------EGAEAAAYNNKLVARHV-PHVPEPVALATKPSVPSIK 402

  Fly   199 ----SSNASLATP----TEPARNRSTGLVRNSAVKVDSKHPLS-------KGQKTDAPMLNYIFD 248
                ..|..:..|    .||:.::.|.:||:..|..|:.|.:|       .|..|...:|..:| 
  Rat   403 EELPLQNFQMDVPGEFSREPSEHQETQMVRSLKVVGDTYHSVSLVWKAPQAGNTTAFSVLYAVF- 466

  Fly   249 TFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQAGSS 286
                       .||      |::|      :||:||.:
  Rat   467 -----------GQR------DMRR------MTVEAGKT 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr20NP_612066.1 IG_like 278..365 CDD:214653 4/9 (44%)
Ig 279..378 CDD:299845 4/8 (50%)
Ig 400..471 CDD:299845
IG_like 402..480 CDD:214653
Lrit1NP_647547.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..128
LRR_8 131..>176 CDD:290566 4/7 (57%)
LRR_4 131..172 CDD:289563 3/3 (100%)
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177 4/8 (50%)
leucine-rich repeat 157..180 CDD:275378 5/11 (45%)
leucine-rich repeat 181..205 CDD:275378 6/26 (23%)
TPKR_C2 201..>240 CDD:301599 8/38 (21%)
Ig 257..345 CDD:299845 16/87 (18%)
IG_like 267..345 CDD:214653 13/77 (17%)
FN3 431..501 CDD:214495 18/75 (24%)
LRR 6 525..548
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.