DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and zig-4

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	288	Identity:	58/288 - (20%)
Similarity:	97/288 - (33%)	Gaps:	93/288 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 PTAHAHIHNQVSTLRSSYEDSDDGVDGDYVIPESQTSTVAILDQDSSMKGQDMESLSLQAGSGTV 156
            |..||.:|:.|.||.:.       :|.:|:...::...||.|:.            :|..|..|.
Worm    18 PPMHAEMHSAVVTLANE-------IDTNYLTSPAKIKIVAPLES------------ALIPGGETY 63

  Fly   157 SPK----SSPDSSGH-KKNASFQQIGSQNVNA---LVPATVATTSSGL---------PSSSNASL 204
            ..:    |:|.::.| |.|....| ||..:|.   |:....|...:|:         ||:.|:
Worm    64 QLRCDIMSTPAATIHWKFNGKLIQ-GSNELNVEEKLLNFGKAIVDTGIVASILTIQCPSAENS-- 125

  Fly   205 ATPTEPARNRSTGLVRNSAVKVDSKHPLSKGQKTDAPMLNYIFDTFSSANKHHHHDQRYGPHFED 269
            .|.:....|....:...:.|:::.:....:.....||.:.:..|:                .||
Worm   126 GTYSCVGYNGHQTIETVAEVEIEGEASGCRSNHKSAPEIVFWTDS----------------RFE- 173

  Fly   270 VQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKR 334
                        ..|:...|.||    .::.|.||..:..:..|:|                ||
Worm   174 ------------MTGNVATLVCR----ANQQVDWVWMSNDELVKNN----------------DK- 205

  Fly   335 YKMEFQYPNNWRLKITNVKKDDEAIYEC 362
                |...:|..|.|.|:..||...|.|
Worm   206 ----FTVLSNGDLVIKNIVWDDMGTYTC 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	20/85 (24%)
		Ig	279..378	CDD:299845	20/84 (24%)
		Ig	400..471	CDD:299845
		IG_like	402..480	CDD:214653
zig-4	NP_509335.1	I-set	47..147	CDD:254352	24/114 (21%)
		Ig	65..144	CDD:143165	17/81 (21%)
		IG_like	176..245	CDD:214653	20/79 (25%)
		Ig	<193..238	CDD:299845	13/58 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900