DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and igcm-2

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	245	Identity:	52/245 - (21%)
Similarity:	89/245 - (36%)	Gaps:	68/245 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 QAGSSIHLNCRISLLQDKTVS--WVRHNTQ----DEGKDNGNALDLL--TVGMHTYTGDKRYKME 338
            :||:.|.|.|.|||..:::.|  | |.:.|    ..|::.|:....|  .:....:.|
Worm    26 KAGAPITLPCSISLFNEESFSLDW-RKDGQLILSAFGQEQGHVTPTLQGRLARDGFLG------- 82

  Fly   339 FQYPNNWRLKITNVKKDDEAIYECQIS------THPPRVIQINLHVNAPKVMIVDEVGDPLQEKY 397
                    :.|.:|...|..:|:|.::      |.|.:.:...|.||.|.|:|.......:.:|
Worm    83 --------ITIHSVTDGDAGVYQCIVTKFSKQPTRPEKGLSAKLVVNVPPVIISPSKNAIIHKK- 138

  Fly   398 YEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSIAKISKTD 462
              :.:.|...|.....  .|..:.|...:.|::                  .:..|:::.:.:.|
Worm   139 --VGADLIFECKAEGA--PSPEITWSRNEQIIS------------------TSPVLTLSNLEEGD 181

  Fly   463 SGNYTC-----------SIS-EFQNFTIVVHILNGESFAELHHGGAVGWH 500
            .|.|||           ||. .|...||:..|...::..|   |..|.||
Worm   182 KGLYTCLAVNIEGNSTSSIDVRFTKATILDLIPLNKTVIE---GSNVFWH 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	21/90 (23%)
		Ig	279..378	CDD:299845	24/109 (22%)
		Ig	400..471	CDD:299845	12/81 (15%)
		IG_like	402..480	CDD:214653	16/89 (18%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653	21/90 (23%)
		Ig	124..200	CDD:386229	14/98 (14%)
		IG_like	214..298	CDD:214653	5/18 (28%)
		Ig_3	309..371	CDD:372822
		Ig	389..467	CDD:386229
		FN3	476..548	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900