DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and Kirrel

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus

Alignment Length:	244	Identity:	59/244 - (24%)
Similarity:	95/244 - (38%)	Gaps:	83/244 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 TVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDK---RYKM---- 337
            ||.||....|.| :.|.....|.|.:              |.|.:||.  .|.|   ||::
Mouse    63 TVVAGQRAVLPC-VLLNYSGIVQWTK--------------DGLALGMG--QGLKAWPRYRVVGSA 110

  Fly   338 -EFQYPNNWRLKITNVKKDDEAIYECQISTH-------------PPRVIQINLHVNAPKVMIVDE 388
             ..||    .|:||:.:..|:|.||||.:..             ||...:|:   ..|.:::  :
Mouse   111 DAGQY----NLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRID---GGPVILL--Q 166

  Fly   389 VGDPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVT-RGGVSVKTELMEDG-ANS 451
            .|.|           ..|:|...|....:::::::        |.| :.|....|||::|| ..:
Mouse   167 AGTP-----------YNLTCRAFNAKPAATIIWFR--------DGTQQEGAVTSTELLKDGKRET 212

  Fly   452 TLSIAKISKTD---SGNYTC-SISEFQNFTIVVHILNGESFA---ELHH 493
            |:|...|..||   ...:|| |::|        .|.||:..:   ::||
Mouse   213 TISQLLIEPTDLDIGRVFTCRSMNE--------AIPNGKETSIELDVHH 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	28/92 (30%)
		Ig	279..378	CDD:299845	31/118 (26%)
		Ig	400..471	CDD:299845	19/76 (25%)
		IG_like	402..480	CDD:214653	20/83 (24%)
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	28/105 (27%)
		Ig2_KIRREL3-like	170..251	CDD:143236	24/107 (22%)
		Ig	255..336	CDD:386229
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810