DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr20 and ntm

DIOPT Version :9

Sequence 1:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	74/308 - (24%)
Similarity:	119/308 - (38%)	Gaps:	76/308 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 NRSTGL-VRNSAVKVDSKHPLSKGQKT--DAPMLNY-IFD----TFSSANKHH------HHDQRY 263
            ||||.| ..|....:|.:..|....|:  ...:.|. |:|    |.|....:|      |...:.
Frog    71 NRSTILYTGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTSRVHLIVQV 135

  Fly   264 GPHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQDKTVSWVRHNTQDEGKDNGNALDLLTVGMHT 328
            .|...|:     ::::.|..||::.|.|..:...:..|:|...:.:..|
Frog   136 PPRIVDI-----SSSIAVNEGSNVSLICIANGRPEPVVNWRYLSPKARG---------------- 179

  Fly   329 YTGDKRYKMEFQYPNNWRLKITNVKKDDEAIYECQIS--THPPRVIQINLHVN-APKVMIVDEVG 390
                  :..|.:|     |:||.:.::...||||..|  ...|.|.::.|.|| .|.::....:|
Frog   180 ------FVSEDEY-----LEITGITREQSGIYECSASNDVSAPDVRRVKLTVNYPPYILDAQNIG 233

  Fly   391 DPLQEKYYEIDSTLQLSCVVRNVAMTSSVVFWKHMDNILNYDVTRGGVSVKTELMEDGANSTLSI 455
            .||..:..       |.|...  |:.::..||...|..|: |..||   ||.|..|  ..|.::.
Frog   234 APLGHRGI-------LQCEAS--AVPAADFFWYKEDKRLS-DSWRG---VKVENRE--TISRVTF 283

  Fly   456 AKISKTDSGNYTC---SISEFQNFTIVVH---------ILNGESFAEL 491
            ..:|:.|.|||||   ::....|.:|::.         :|..||.|.|
Frog   284 LNVSEQDYGNYTCMAKNLLGHSNASIILFELFQSTSSPLLQEESTAAL 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	17/86 (20%)
		Ig	279..378	CDD:299845	21/100 (21%)
		Ig	400..471	CDD:299845	22/73 (30%)
		IG_like	402..480	CDD:214653	24/80 (30%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	16/61 (26%)
		IG_like	45..133	CDD:214653	16/61 (26%)
		IG_like	143..220	CDD:214653	21/103 (20%)
		IGc2	150..209	CDD:197706	17/85 (20%)
		ig	227..311	CDD:278476	27/98 (28%)
		IG_like	230..311	CDD:214653	27/95 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000