DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dci and CDY1

DIOPT Version :9

Sequence 1:	NP_612065.1	Gene:	Dci / 38100	FlyBaseID:	FBgn0035169	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_004671.1	Gene:	CDY1 / 9085	HGNCID:	1809	Length:	554	Species:	Homo sapiens

Alignment Length:	240	Identity:	70/240 - (29%)
Similarity:	124/240 - (51%)	Gaps:	14/240 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YKELLVEQQ-GKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGND 69
            |::::|::: |...:.......:||.:|....:|:...|.....|:. .:|:|:..|.:|..|.|
Human   283 YRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDS-KLVLFSAAGSVFCCGLD 346

  Fly    70 -------LSQSSNTDDIDAFFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCDVAW 127
                   |..:.||..::..     .|.|..|.:|:..:|.::..|||||||:||:|:.|||:.|
Human   347 FGYFVKHLRNNRNTASLEMV-----DTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVW 406

  Fly   128 CSETTYFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASEL 192
            .:|..:|.||:|..|..|:|.||...|.::|::.|:|:|:....|:|:||.....||::|.....
Human   407 ANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTF 471

  Fly   193 ESVIWPKLRQYSELPTNSLLQGKRLVKDGFLENLIKANEAECKQL 237
            ...:..::::.:......|.:.|.||:......|.:|||.||:.|
Human   472 TQEVMIQIKELASYNPIVLEECKALVRCNIKLELEQANERECEVL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	crotonase-like	9..197	CDD:119339	58/195 (30%)
CDY1	NP_004671.1	CHROMO	5..58	CDD:214605
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	76..106
		crotonase-like	286..482	CDD:119339	58/201 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	155	1.000	Domainoid score	I4209
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1471901at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42274
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.880