DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dci and DCI1

DIOPT Version :9

Sequence 1:	NP_612065.1	Gene:	Dci / 38100	FlyBaseID:	FBgn0035169	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_014823.3	Gene:	DCI1 / 854352	SGDID:	S000005706	Length:	271	Species:	Saccharomyces cerevisiae

Alignment Length:	243	Identity:	63/243 - (25%)
Similarity:	109/243 - (44%)	Gaps:	35/243 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSG------NDLSQS 73
            |...:.|..:||..|.:....:..:..:|.:.||.:.|...|....|..|:||      |.|:..
Yeast    11 GPFFIIKLIDPKHLNSLTFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFSSGGKFSAVNKLNDG 75

  Fly    74 SNTDDIDAFFKQSNATFKAMVL---SFVNCRKIVLALVNGPAIGIGATIVGLCDVAWC-SETTYF 134
            ..|.:::...|..:|.....:.   :|...:|:::..:||||||:.|::|.|||:.:. :::.:.
Yeast    76 DVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAIGLSASLVALCDIVYSQNDSVFL 140

  Fly   135 YTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEA--------YQFNFVSRIFKASE 191
            ..||:.||.|.|.|:|..|...||.:.|:|.::.|.|:..:|.        ||.. .:..|....
Yeast   141 LFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELIGTIITKNYQLT-NTETFNEKV 204

  Fly   192 LESV------IWPKLRQYSELPTNSLLQGKRLVKDGFLENLIKANEAE 233
            |:.:      ::||          |:|..|.|:.....:.||||...|
Yeast   205 LQDIKQNLEGLYPK----------SVLGMKELLHSEMKQKLIKAQAME 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	crotonase-like	9..197	CDD:119339	52/205 (25%)
DCI1	NP_014823.3	CaiD	1..264	CDD:223955	63/243 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346018
Domainoid	1	1.000	78	1.000	Domainoid score	I2062
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I1537
Isobase	1	0.950	-	0	Normalized mean entropy	S2085
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003208
OrthoInspector	1	1.000	-	-		otm46964
orthoMCL	1	0.900	-	-		OOG6_103916
Panther	1	1.100	-	-	LDO	PTHR43684
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.740