DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dci and ECI1

DIOPT Version :9

Sequence 1:	NP_612065.1	Gene:	Dci / 38100	FlyBaseID:	FBgn0035169	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_013386.1	Gene:	ECI1 / 850990	SGDID:	S000004274	Length:	280	Species:	Saccharomyces cerevisiae

Alignment Length:	267	Identity:	66/267 - (24%)
Similarity:	119/267 - (44%)	Gaps:	20/267 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QGKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGNDLS--QSSNT 76
            :|...:....||...|.:....|..:..:|...:.:..|...:....|..|:||.|..  ..:..
Yeast    16 EGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 80

  Fly    77 DDIDAFFKQSNATFKAMVL-------SFVNCRKIVLALVNGPAIGIGATIVGLCDVAW-CSETTY 133
            ||.:.:..:::......|.       :|:...|:::..:||||||:.|.:|.|||:.: .::..|
Yeast    81 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVY 145

  Fly   134 FYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIF-----KASELE 193
            ...||..|||:.|||::..|||..|.:...|.|:.::|.......:..|:|:.|     .|....
Yeast   146 LLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFN 210

  Fly   194 SVIWPKLRQYSE---LPTNSLLQGKRLVKDGFLENLIKANEAECKQLLQQFQHPEFAQAIIDFAS 255
            :.:..:||:..:   ||  |.|..|:|:|...::...|||..|..:.|:.:...|..:......|
Yeast   211 AKVLEELREKVKGLYLP--SCLGMKKLLKSNHIDAFNKANSVEVNESLKYWVDGEPLKRFRQLGS 273

  Fly   256 RKNKAKL 262
            ::.|.:|
Yeast   274 KQRKHRL 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	crotonase-like	9..197	CDD:119339	48/197 (24%)
ECI1	NP_013386.1	CaiD	6..243	CDD:223955	57/228 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346015
Domainoid	1	1.000	78	1.000	Domainoid score	I2062
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H74357
Inparanoid	1	1.050	91	1.000	Inparanoid score	I1537
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003208
OrthoInspector	1	1.000	-	-		otm46964
orthoMCL	1	0.900	-	-		OOG6_103916
Panther	1	1.100	-	-	O	PTHR43684
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3644
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.820