DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dci and hadhab

DIOPT Version :9

Sequence 1:	NP_612065.1	Gene:	Dci / 38100	FlyBaseID:	FBgn0035169	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001082906.1	Gene:	hadhab / 793834	ZFINID:	ZDB-GENE-041111-204	Length:	763	Species:	Danio rerio

Alignment Length:	258	Identity:	60/258 - (23%)
Similarity:	108/258 - (41%)	Gaps:	24/258 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 EQQGKLLVAKFNNPKKKNCINRVAYQ---EMTRVLTEVNDDEGV-TIVVFTGVGDIFTSGNDLSQ 72
            |.:|.:.|.:.|:|..|  :|.::.|   :||.|:.||..:..| ::|:.:.....|.:|.|:|.
Zfish    44 EVKGDVAVVRMNDPTAK--VNTLSVQMQKDMTEVMDEVWGNSAVQSVVLISSKPGCFIAGADISM 106

  Fly    73 ---SSNTDDIDAFFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCD--VAWCSETT 132
               ....:::....::....|:.:..|    .|.::|.:||..:|.|......|.  :|..|:.|
Zfish   107 IKACKTAEEVTGLSQEGQRMFEKIEKS----PKPIVAAINGSCLGGGLEFAIACQYRIATKSKKT 167

  Fly   133 YFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASELESVIW 197
            ....|...|||:|..|.:..||.:||...|.:::|....:.|.:|.:...|      .:|...:.
Zfish   168 VLGCPEVMLGLLPGAGGTQRLPKMLGLPSAFDVMLTGRSIRADKAKKMGLV------HQLVDTLG 226

  Fly   198 PKLRQYSELPTNSLLQGKRLVKDGFLENLIK-ANEAECKQLLQQF--QHPEFAQAIIDFASRK 257
            |.|:...|.....|.:.......|..:..|. ..|....|.:|.:  .:|...|.|.:...:|
Zfish   227 PGLKSPEERTIEYLEEVAVEAARGLAQKKITLTKEKGWMQKIQDYVMSYPFVRQQIYNTVEKK 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	crotonase-like	9..197	CDD:119339	47/193 (24%)
hadhab	NP_001082906.1	fa_ox_alpha_mit	27..762	CDD:131494	60/258 (23%)
		crotonase-like	41..251	CDD:119339	51/218 (23%)
		3HCDH_N	363..541	CDD:280833
		3HCDH	544..639	CDD:279114
		3HCDH	676..>750	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900