DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dci and Ehhadh

DIOPT Version :9

Sequence 1:	NP_612065.1	Gene:	Dci / 38100	FlyBaseID:	FBgn0035169	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_076226.2	Gene:	Ehhadh / 74147	MGIID:	1277964	Length:	718	Species:	Mus musculus

Alignment Length:	265	Identity:	55/265 - (20%)
Similarity:	102/265 - (38%)	Gaps:	41/265 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGNDLSQSSNTDDIDA 81
            |.:.:..|| ..|.|:.....|:...|.:.:.|..|..:|..|..|.|.:|         .||..
Mouse    11 LAMIRLCNP-PVNAISPTVITEVRNGLQKASLDHTVRAIVICGANDNFCAG---------ADIHG 65

  Fly    82 FFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCDVAWCSETTYFYTPFTKLGLVPE 146
            |...:..|..::|......:|.|:|.:.|.|:|.|..:...|.....:.......|...||::|.
Mouse    66 FKSPTGLTLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPG 130

  Fly   147 GGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASELESVIWPKLRQYSELPTNSL 211
            ...:.:||.::|...|.:::.....:|..||.:...:..:.|:..:|..|     ::::......
Mouse   131 ARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEEAI-----KFAQTVIGKP 190

  Fly   212 LQGKRLVK----------DGFLENLIK---------ANEAECKQLLQQFQHPEFAQAIIDFASRK 257
            ::.:|::.          ..|.|.:.|         |.|...:.:....:|| :..||      |
Mouse   191 IEPRRILNKPVPSLPNMDSVFAEAIAKVRKQYPGRLAPETCVRSVQASVKHP-YEVAI------K 248

  Fly   258 NKAKL 262
            .:|||
Mouse   249 EEAKL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	crotonase-like	9..197	CDD:119339	40/179 (22%)
Ehhadh	NP_076226.2	Enoyl-CoA hydratase / isomerase	1..280		55/265 (21%)
		crotonase-like	12..186	CDD:119339	40/188 (21%)
		fadJ	20..702	CDD:236864	52/255 (20%)
		3-hydroxyacyl-CoA dehydrogenase	281..567
		3HCDH_N	297..471	CDD:280833
		3HCDH	473..577	CDD:279114
		3HCDH	614..700	CDD:279114
		Microbody targeting signal. /evidence=ECO:0000250	716..718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900