DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dci and ech-4

DIOPT Version :9

Sequence 1:	NP_612065.1	Gene:	Dci / 38100	FlyBaseID:	FBgn0035169	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001366707.1	Gene:	ech-4 / 174665	WormBaseID:	WBGene00001153	Length:	385	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	84/256 - (32%)
Similarity:	137/256 - (53%)	Gaps:	5/256 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLVEQQGKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGNDLSQ- 72
            |.|.::||:.....|.|||.|.:....||.:.:.|...|:|:..:|.|.|..|..:.:||||:.
Worm   129 LSVTREGKVFKIALNRPKKFNALTLEMYQGIQKALEVSNNDKSTSITVITANGSYYCAGNDLTNF 193

  Fly    73 ----SSNTDDIDAFFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCDVAWCSETTY 133
                ....:.|......:....|..|.:::|..|.::||:||||:||..|::|:.|....::...
Worm   194 KAAAGGTKEQIADMANTAKVIMKDYVNAYINHEKPLIALINGPAVGIAVTVLGMFDYVIATDKAS 258

  Fly   134 FYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASELESVIWP 198
            |:|||..||..|||.|||..|||:|..:|||:||:.:.:|||.|..:..|:.:...:|.:|....
Worm   259 FHTPFAPLGQSPEGVSSYTFPLIMGSLRASEMLLVCKKISAQTAKDYGLVNEVVPDAEFQSHAQK 323

  Fly   199 KLRQYSELPTNSLLQGKRLVKDGFLENLIKANEAECKQLLQQFQHPEFAQAIIDFASRKNK 259
            .:..:|:||..:|...|:|::....|.|::.|..|..|:.:::|..|..|||..|.::..|
Worm   324 TVEAFSQLPPETLRINKKLLRSLHKEKLLEVNNIEADQICERWQSKECHQAIAAFMTKGAK 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	crotonase-like	9..197	CDD:119339	66/192 (34%)
ech-4	NP_001366707.1	ACBP	25..109	CDD:238248
ech-4	NP_001366707.1	crotonase-like	129..326	CDD:119339	66/196 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	149	1.000	Domainoid score	I2715
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	151	1.000	Inparanoid score	I2960
Isobase	1	0.950	-	0	Normalized mean entropy	S2085
OMA	1	1.010	-	-		QHG58780
OrthoDB	1	1.010	-	-		D1471901at2759
OrthoFinder	1	1.000	-	-		FOG0003208
OrthoInspector	1	1.000	-	-		otm14061
orthoMCL	1	0.900	-	-		OOG6_103916
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3644
SonicParanoid	1	1.000	-	-		X3113
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.760