DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dci and eci2

DIOPT Version :9

Sequence 1:	NP_612065.1	Gene:	Dci / 38100	FlyBaseID:	FBgn0035169	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_012819853.2	Gene:	eci2 / 100216270	XenbaseID:	XB-GENE-961246	Length:	413	Species:	Xenopus tropicalis

Alignment Length:	259	Identity:	93/259 - (35%)
Similarity:	146/259 - (56%)	Gaps:	3/259 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YQGYKELLVEQQGKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSG 67
            ::.|:.:.|.::..::....|.|:|||.|....|:|:...|.|...||.| ..|.:|.||.|.||
Frog   155 HKKYETIQVSREDNIIKIFLNRPEKKNAITLTMYKEIGEALEEAGKDESV-FAVLSGFGDYFCSG 218

  Fly    68 NDLSQSSN--TDDIDAFFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCDVAWCSE 130
            |||:..:|  .:..:...|.|....:..|..|::..|.::|:|||||.||..||:||.|:.:.::
Frog   219 NDLNNFTNIPPEGKEKMAKDSADLLETFVSKFIDFPKPLIAVVNGPATGISVTILGLFDLVYATD 283

  Fly   131 TTYFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASELESV 195
            ...|:|||::||..|||.|||..|.|:|..||:|:||.::.|:||||.....|:.:|.....:..
Frog   284 RATFHTPFSQLGQSPEGCSSYTFPRIMGLGKATEMLLFNKKLTAQEACNLGLVAEVFPDGSFQKE 348

  Fly   196 IWPKLRQYSELPTNSLLQGKRLVKDGFLENLIKANEAECKQLLQQFQHPEFAQAIIDFASRKNK 259
            :|.:::.||.||.|||...|:|::....|.|...|..||::|.:::...|...|||.|..::.|
Frog   349 VWERIKDYSTLPKNSLAFSKQLIRVNEKEKLHAVNIQECERLKERWLSEECMNAIISFFQKRAK 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	crotonase-like	9..197	CDD:119339	70/189 (37%)
eci2	XP_012819853.2	ACBP	60..131	CDD:412233
eci2	XP_012819853.2	crotonase-like	161..411	CDD:419961	91/250 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I3827
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I3989
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1471901at2759
OrthoFinder	1	1.000	-	-		FOG0003208
OrthoInspector	1	1.000	-	-		otm49505
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3644
SonicParanoid	1	1.000	-	-		X3113
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.090