Protein Alignment JMJD5 and JMJD7

DIOPT Version :10

• Sequence 1: NP_612063.2
• Gene: JMJD5 / 38097
• FlyBaseID: FBgn0035166
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_001108104.1
• Gene: JMJD7 / 100137047
• HGNCID: 34397
• Length: 316
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 68/283 - (24%)
• Similarity: 108/283 - (38%)
• Gaps: 62/283 - (21%)

  Fly   163 IPQLDAPSLE-EFQTKCFEAGQPTLLLNTIQHWPALHKWLDLNYLLQVAGNRTVPIEIGSNYASD 226
            :|.||.|... .|........:|.::.|.:||||||.|| .|.|.....|:..|.:.:..:..:|
Human    29 VPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKW-SLPYFRATVGSTEVSVAVTPDGYAD 92

  Fly   227 -----------EWSQQLVKIRD------------FLSRQFGKEPSKAGQNIEYLAQHELFAQIPA 268
                       |....|..:.|            ::.:|....||:..|.:..|..|     :|.
Human    93 AVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESH-----VPW 152

  Fly   269 LKEDISIPDYCTISNEDTPGAVDIKAWLGPAGTVSPMHYDPKHNLLCQVFGSKRIILAAPADTD- 332
            ..|.:.          ..|.||:.  |||.|..|:.:|.|...||.|.|.|.|..:...|:|..
Human   153 ASEALG----------KMPDAVNF--WLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPF 205

  Fly   333 ---NLYPH--------------DSEFLANTARIDAAQLDPE--TYPLVAKVKFYQLLLQPGDCLY 378
               .||..              |.|.:.....|....|.|:  .||..::.:..:..::.|:.||
Human   206 IPYELYTPATYQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGEMLY 270

  Fly   379 MPPKWWHYVRSEAPSFSVSFWWE 401
            :|..|:|:|:......:|:||::
Human   271 LPALWFHHVQQSQGCIAVNFWYD 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JMJD5	NP_612063.2	Cupin_8	172..401	CDD:463936	64/272 (24%)
JMJD7	NP_001108104.1	Cupin_8	38..297	CDD:463936	64/274 (23%)