DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13887 and BCAP31

DIOPT Version :9

Sequence 1:	NP_001286891.1	Gene:	CG13887 / 38096	FlyBaseID:	FBgn0035165	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_001132929.1	Gene:	BCAP31 / 10134	HGNCID:	16695	Length:	313	Species:	Homo sapiens

Alignment Length:	238	Identity:	95/238 - (39%)
Similarity:	151/238 - (63%)	Gaps:	21/238 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLVWTLIAGFLYAEIALVLLLVLPVLTPYRWNRFFKSKFLSMLGQQAHIYFLLIMGILVIFLLE 65
            |||.||.:|.|||||:.:||||.:|.::|.||.:.|||:.:.:|....:.:|::::.|||:.:::
Human    68 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILVLLVID 132

  Fly    66 AIREMRKYSGLQQSNEVHLNV-EMQH-SMKLFRAQRNFYISGFAIFLALVIRRLVNLICTQANLM 128
            |:||:|||..:.:...:..|. .|:| .|||||||||.||:||::.|:.::||||.||..||.|:
Human   133 AVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLL 197

  Fly   129 AQSEASFKQAQSATAAARSLLENKNTEKAKEAGEDTTLIELN----KLRERVQELTSDLNR---- 185
            |.:||..|||:||:.||:..:| :|.:..|.|..|...:::.    ||.|..:.|.:||.:
Human   198 ASNEAFKKQAESASEAAKKYME-ENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDE 261

  Fly   186 --------EKKDKE--AVKSQAESINREYDRLTEEYSKLQKKI 218
                    ||.:.:  |::.|:|.:.:|||||.||::|||..:
Human   262 LASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAV 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13887	NP_001286891.1	Bap31	1..205	CDD:283239	86/223 (39%)
BCAP31	NP_001132929.1	Bap31	68..291	CDD:283239	86/223 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159948
Domainoid	1	1.000	126	1.000	Domainoid score	I5417
eggNOG	1	0.900	-	-		E1_KOG1962
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38095
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4174
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55985
OrthoDB	1	1.010	-	-		D1514108at2759
OrthoFinder	1	1.000	-	-		FOG0002712
OrthoInspector	1	1.000	-	-		otm40604
orthoMCL	1	0.900	-	-		OOG6_102592
Panther	1	1.100	-	-	LDO	PTHR12701
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3116
SonicParanoid	1	1.000	-	-		X2501
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.800