Protein Alignment CG42553 and C7orf25

DIOPT Version :10

• Sequence 1: NP_612060.2
• Gene: CG42553 / 38094
• FlyBaseID: FBgn0260755
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_047276783.1
• Gene: C7orf25 / 79020
• HGNCID: 21703
• Length: 435
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 142/404 - (35%)
• Similarity: 212/404 - (52%)
• Gaps: 52/404 - (12%)

  Fly    14 AHKKVKLGEELKKALKDFEDLPGVSKVQRKIQQELKFLNKVITTR-SVKEHHITSSNFVYYDFLI 77
            |.:.:|..|.|.::.|.  .:.|.:|:..|::.|||||.||...: ::||.|:.|:|..:...::
Human    28 AKELIKRAESLSRSRKG--GIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIV 90

  Fly    78 KTLRLQQGVVDINAVFRLE---SRDSPLRVDIVANNGLKWVKVIARNSKSVEDAARGCVSIGARS 139
            ::....:.||.:..||...   .....|.||:|||.|..|||.|.|.::::.:...|....|.:|
Human    91 ESAENLEEVVSVLHVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKS 155

  Fly   140 VIDQAEDYLEASELSFCMFQRPKIVFYFSNKIEDSLHEELMEMGVQ--------TASLDSPD--- 193
            :|:||||:|:||......:..|.|:|.|.|.:...:.|:|.|||:.        .|.||.|:
Human   156 IIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNALLDHPEELQ 220

  Fly   194 ----------------TDLD-------------MYATTSNELNLDVTTLLAYVSALTNGSANWVY 229
                            |.:|             :.......:|||:|||:.|||||:.|..::::
Human   221 PSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIF 285

  Fly   230 KEPLLTEQAERERASPLKPLLEKILEGKTLVCCQLAYDAFQSILDIVGGEGERKRAEELMKRVTV 294
            ||.:||||||:||...:.|.||..::.|.|..|:.|...||||||.:||.|||:||..|:||:.|
Human   286 KEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERATVLIKRINV 350

  Fly   295 YPDVETIPEEFSHIRFTAN--VNERSLKIFSFGMARQIFTVTSNKAFVRSAKMQGINVPVFVHAS 357
            .||.   |.|.: :|..|:  :|.|||.||..|...:..|:|:|..|||:|..||:...||:|..
Human   351 VPDQ---PSERA-LRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQP 411

  Fly   358 VALTEGKQATGRPL 371
            .||||.|:|...||
Human   412 RALTESKEALATPL 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42553	NP_612060.2	DUF5614	36..184	CDD:436527	51/151 (34%)
		DUF1308	206..369	CDD:399767	77/164 (47%)
C7orf25	XP_047276783.1	DUF5614	15..232	CDD:436527	61/205 (30%)
		DUF1308	262..423	CDD:399767	77/164 (47%)