Protein Alignment Sf3b3 and sf3b3

DIOPT Version :9

• Sequence 1: NP_728546.1
• Gene: Sf3b3 / 38093
• FlyBaseID: FBgn0035162
• Length: 1227
• Species: Drosophila melanogaster
• Sequence 2: NP_998668.1
• Gene: sf3b3 / 406824
• ZFINID: ZDB-GENE-040426-2901
• Length: 1217
• Species: Danio rerio
• Alignment Length: 1230
• Identity: 915/1230 - (74%)
• Similarity: 1066/1230 - (86%)
• Gaps: 16/1230 - (1%)

  Fly     1 MYLYNLTLQKATGVTHAVHGNFSGGKQQEVLLSRGKSLELLRPDSNTGKVHTLLSTEIFGCVRAL 65
            |:|||:|||:|||::||:||||||.||||:::||||.|||||||:|||||||||:.|:||.||:|
Zfish     1 MFLYNITLQRATGISHAIHGNFSGTKQQEIVVSRGKILELLRPDANTGKVHTLLTMEVFGVVRSL 65

  Fly    66 MAFRLTGGTKDYIVVGSDSGRIVILEYNPSKNALEKVHQETFGKSGCRRIVPGQYFAIDPKGRAV 130
            ||||||||||||:||||||||||||||:||||..||:|||||||||||||||||:.|:|||||||
Zfish    66 MAFRLTGGTKDYVVVGSDSGRIVILEYHPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAV 130

  Fly   131 MIGAVEKQKLAYIMNRDTQARLTISSPLEAHKSNTLTYHMVGVDVGFDNPMFACLEIDYEEADMD 195
            |:||.|||||.||:|||..|||||||||||||:|||.||:|||||||:||||||||:||||||.|
Zfish   131 MMGATEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADND 195

  Fly   196 PSGDAAQRTQQTLTFYELDLGLNHVVRKYSEPLEEHANFLVSVPGGNDGPSGVLICSENYLTYKN 260
            |:|:||..|||||||||||||||||||||||.||||.|||::||||:|||||||||||||:||||
Zfish   196 PTGEAAANTQQTLTFYELDLGLNHVVRKYSEALEEHGNFLITVPGGSDGPSGVLICSENYITYKN 260

  Fly   261 LGDQHDIRCPIPRRRNDLDDPERGMIFICSATHRTKSMYFFLLQTEQGDIFKITLETDDDVVSEI 325
            .|||.||||||||||||||||||||||:|||||:||||:|||.|||||||||:|||||:::|:||
Zfish   261 FGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKVTLETDEEMVTEI 325

  Fly   326 KLKYFDTVPPATAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDDEPEFSSAMPLEEGETFFFAPR 390
            ::|||||:|.||||||||||||||:||||||||||||||||||:|||||||||||||:||||.||
Zfish   326 RMKYFDTIPVATAMCVLKTGFLFVSSEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPR 390

  Fly   391 ALKNLVLVDELPSFAPIITSQVADLANEDTPQLYVLCGRGPRSTLRVLRHGLEVSEMAVSELPGN 455
            .|||||||||..|.:||::.|:|||||||||||||.|||||.|||||||||||||||||||||||
Zfish   391 PLKNLVLVDEQESLSPIMSCQIADLANEDTPQLYVACGRGPGSTLRVLRHGLEVSEMAVSELPGN 455

  Fly   456 PNAVWTVKKRADDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLCCAALGDDALVQVY 520
            |||||||::..:|||||||||||||||||||||||||||||||||||||||.|:.||:|||||||
Zfish   456 PNAVWTVRRHVEDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGEDALVQVY 520

  Fly   521 PDGIRHIRSDKRVNEWKAPGKKSITKCAVNQRQVVITLSGRELVYFEMDPTGELNEYTERSEMPA 585
            ||||||||:||||||||.||||:|.:||||||||||.|:|.|||||||||:|:|||||||.||.|
Zfish   521 PDGIRHIRADKRVNEWKTPGKKTIIRCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSA 585

  Fly   586 EIMCMALGTVPEGEQRSWFLAVGLADNTVRILSLDPNNCLTPCSMQALPSPAESLCLVEMGHTES 650
            :::||:|..||.|||||.||||||.||||||:||||::||.|.||||||:..||||:||||..|.
Zfish   586 DVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGVEK 650

  Fly   651 TTQGGLDDDAPAQRSGNNKGTI---YLNIGLSNGVLLRTVLDPVSGDLADTRTRYLGSRPVKLFR 712
            ..:.|            .||||   ||||||.||||||||||||:|||:||||||||||||||||
Zfish   651 QDELG------------EKGTICFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFR 703

  Fly   713 IKMQGSEAVLAMSSRTWLSYYHQNRFHLTPLSYETLEYASGFSSEQCSEGIVAISTNTLRILALE 777
            ::|||.|||||||||:||||.:|:||||||||||||||||||:||||.|||||||||||||||||
Zfish   704 VRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEYASGFASEQCPEGIVAISTNTLRILALE 768

  Fly   778 KLGAVFNQVAFPLQYTPRTFVIHPDTGRMLIAETDHNAYTEDTKSARKEQMAEEMRSAAGDEERE 842
            ||||||||||||||||||.|||||:|..:::.|||||||||.||:.||:||||||..|||::|||
Zfish   769 KLGAVFNQVAFPLQYTPRKFVIHPETNNLILIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERE 833

  Fly   843 LAREMANAFINEVLPEDVFSSPKAGLGLWASQIRCLDAMHGQTMFSVPLTQNEAIMSMAMLKFSI 907
            ||.|||.||:||.|||.:|.:||||.|.|||.:|.::.:.|.|:..|.|.||||..|:|:.:|..
Zfish   834 LAAEMAAAFLNENLPEAIFGAPKAGSGQWASLVRLINPIQGNTLDLVQLEQNEAAFSVAICRFLN 898

  Fly   908 AADGRYYLAVGIAKDLQLNPRISQGGCIDIYKIDPTCSSLEFMHRTDIDEIPGALCGFQGRLLAG 972
            ..|. :|:.||:|:|:.||||...||.|..|:|......|||:|:|.::::|.|:..||||:|.|
Zfish   899 GGDD-WYVLVGVARDMILNPRSVGGGYIYTYRIVGGGDKLEFLHKTPVEDVPLAIAPFQGRVLVG 962

  Fly   973 CGRMLRIYDFGKKKMLRKCENKHIPYQIVNIQAMGHRVYVSDVQESVFFIRYRRAENQLIIFADD 1037
            .|::|||||.||||:||||||||:|..:..|..:|.||.|||||||:|::||||.||||||||||
Zfish   963 VGKLLRIYDLGKKKLLRKCENKHVPNLVTGIHTIGQRVIVSDVQESLFWVRYRRNENQLIIFADD 1027

  Fly  1038 THPRWVTATTLLDYDTIAIADKFGNLSIQRLPHSVTDDVDEDPTGTKSLWDRGLLSGASQKSENI 1102
            |:|||:|...||||||:|.||||||:.:.|||.:.:|||||||||.|:|||||||:|||||:|.|
Zfish  1028 TYPRWITTACLLDYDTMASADKFGNICVVRLPPNTSDDVDEDPTGNKALWDRGLLNGASQKAEII 1092

  Fly  1103 CSFHVGEIIMSLQKATLIPGGSEALIYATLSGTVGAFVPFTSREDYDFFQHLEMHMRNENPPLCG 1167
            .::|:||.::||||.||||||||:|:|.||||.:|..|||||.||:|||||||||||:|.|||||
Zfish  1093 INYHIGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDFFQHLEMHMRSEFPPLCG 1157

  Fly  1168 RDHLSYRSSYYPVKNVLDGDLCEQYLSIEAAKQKSIAGDMFRTPNQICKKLEDIRTRYAF 1227
            |||||:||.|:|||||:|||||||:.|::..||||::.::.|||.::.||||||||||||
Zfish  1158 RDHLSFRSYYFPVKNVIDGDLCEQFNSMDPHKQKSVSEELDRTPPEVSKKLEDIRTRYAF 1217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sf3b3	NP_728546.1	MMS1_N	76..592	CDD:402179	431/515 (84%)
		CPSF_A	872..1194	CDD:397339	198/321 (62%)
sf3b3	NP_998668.1	MMS1_N	76..592	CDD:287414	431/515 (84%)
		CPSF_A	863..1182	CDD:281209	197/319 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596500
Domainoid	1	1.000	912	1.000	Domainoid score	I47
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6579
Inparanoid	1	1.050	1844	1.000	Inparanoid score	I59
OMA	1	1.010	-	-		QHG54483
OrthoDB	1	1.010	-	-		D57158at33208
OrthoFinder	1	1.000	-	-		FOG0004388
OrthoInspector	1	1.000	-	-		oto41281
orthoMCL	1	0.900	-	-		OOG6_102496
Panther	1	1.100	-	-	LDO	PTHR10644
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1253
SonicParanoid	1	1.000	-	-		X3106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940